Table 6 Binary and multivariable logistic regression of factors associated with adherence to H. pylori eradication therapy in the hospitals in Hawassa city, February–June 2023 (n = 291)
Variable | Category | Adherence | COR (CI: 95%) | P-value | AOR (CI: 95%) | P-value | |
|---|---|---|---|---|---|---|---|
Adhered | Not-adhered | ||||||
Sex | Male | 77 | 17 |  |  | – | – |
Female | 153 | 44 | 1.30 (0.70, 2.43) | 0.41 | – | – | |
Age (years) | 18–24 | 60 | 19 | – | – | – | – |
25–34 | 86 | 19 | 0.60 (0.18, 1.97) | 0.40 | – | – | |
35–44 | 41 | 11 | 0.86 (0.26, 2.80) | 0.80 | – | – | |
45–54 | 22 | 8 | 0.71 (0.20, 2.50) | 0.59 | – | – | |
> 54 | 21 | 4 | 0.52 (0.14, 2.00) | 0.34 | – | – | |
Residence | Rural | 122 | 40 | – | – | – | – |
Urban | 108 | 21 | 1.69 (0.93, 3.03) | 0.08 | 0.49 (0.23, 1.01) | 0.52 | |
Educational status | Illiterate | 28 | 6 | – | – | – | – |
Primary school | 25 | 7 | 1.47 (0.56, 3.84) | 0.43 | 0.77 (0.21, 2.85) | 0.69 | |
Secondary school | 69 | 14 | 1.12 (0.45, 2.83) | 0.80 | 1.48 (0.48, 4.63) | 0.50 | |
College and above | 108 | 34 | 1.55 (0.78, 3.10) | 0.21 | 0.85 (0.30, 2.48) | 0.77 | |
History of gastritis | No | 94 | 24 | – | – | – | – |
Yes | 136 | 37 | 1.066 (0.60, 1.90) | 0.83 | – | – | |
History of H. pylori status | Not known | 102 | 27 | – | – | – | – |
Positive | 40 | 7 | 1.16 (0.63, 2.12) | 0.63 | 0.92 (0.46, 1.81) | 0.83 | |
Negative | 88 | 27 | 1.753 (0.70, 4.36) | 0.23 | 1.79 (0.69, 4.69) | 0.23 | |
History of eradication therapy | No | 205 | 56 | – | – | – | – |
Yes | 25 | 5 | 0.73 (0.27, 2.00) | 0.54 | – | – | |
Duration of illness | Less than a month | 77 | 15 | – | – | – | – |
More than a month | 153 | 46 | 1.54 (0.81, 2.94) | 0.19 | 0.54 (0.27, 1.08) | 0.08 | |
History of other illnesses | No | 144 | 38 | – | – | – | – |
Yes | 86 | 23 | 1.01 (0.57, 1.81) | 0.97 | – | – | |
History of alcohol intake | No | 37 | 9 | – | – | – | – |
Yes | 193 | 52 | 1.11 (0.50, 2.44) | 0.80 | – | – | |
History traditional medicine use | No | 199 | 57 | – | – | – | – |
Yes | 31 | 44 | 0.45 (0.15, 1.33) | 0.15 | 2.35 (0.74, 7.45) | 0.15 | |
Eradication regimen used | OAC for 14-days | 217 | 54 | – | – | – | – |
OAC for 10-days | 13 | 7 | 2.16 (0.82, 5.68) | 0.12 | 0.40 (0.14, 1.12) | 0.08 | |
Regimen completeness | Complete | 163 | 44 | – | – | – | – |
Incomplete | 67 | 17 | 0.94 (0.50, 1.76) | 0.85 | – | – | |
Adverse effect self-report | Present | 106 | 37 | – | – | – | – |
Absent | 124 | 24 | 1.80 (1.01, 3.21) | 0.04 | 2.45 (1.29, 4.62) | 0.006 | |