Articles
Page 15 of 15
-
Citation: Gut Pathogens 2010 2:25
-
Epigenome targeting by probiotic metabolites
The intestinal microbiota plays an important role in immune development and homeostasis. A disturbed microbiota during early infancy is associated with an increased risk of developing inflammatory and allergic...
Citation: Gut Pathogens 2010 2:24 -
Stress-induced survival strategies enable Salmonella Enteritidis to persistently colonize the chicken oviduct tissue and cope with antimicrobial factors in egg white: A hypothesis to explain a pandemic
Egg-associated transmission to humans seems to be characteristic of the Salmonella serotype Enteritidis, explaining why this particular serotype has caused a worldwide pandemic since the mid '80s. Salmonella Ente...
Citation: Gut Pathogens 2010 2:23 -
Campylobacter jejuni isolates in Finnish patients differ according to the origin of infection
Campylobacter jejuni is a significant cause of bacterial enteritis worldwide. Very little is known about the pathogenicity mechanisms and virulence factors of this important enteropathogen. C. jejuni isolates fro...
Citation: Gut Pathogens 2010 2:22 -
Ulcerative colitis and Crohn's disease: is Mycobacterium avium subspecies paratuberculosis the common villain?
Mycobacterium avium, subspecies paratuberculosis (MAP) causes a chronic disease of the intestines in dairy cows and a wide range of other animals, including nonhuman primates, called Johne's ("Yo-knee's") disease...
Citation: Gut Pathogens 2010 2:21 -
Compatible solutes: the key to Listeria's success as a versatile gastrointestinal pathogen?
Recently we reported a role for compatible solute uptake in mediating bile tolerance and increased gastrointestinal persistence in the foodborne pathogen Listeria monocytogenes[1]. Herein, we review the evolution...
Citation: Gut Pathogens 2010 2:20 -
Luminal and mucosal-associated intestinal microbiota in patients with diarrhea-predominant irritable bowel syndrome
Recent studies have suggested a role for an altered intestinal microbiota in the pathophysiology of irritable bowel syndrome (IBS). However, no consensus has been reached regarding the association between spec...
Citation: Gut Pathogens 2010 2:19 -
Antimicrobial resistance patterns and prevalence of class 1 and 2 integrons in Shigella flexneri and Shigella sonnei isolated in Uzbekistan
Shigella is a frequent cause of bacterial dysentery in the developing world. Treatment with effective antibiotics is recommended for shigellosis, but options become limited due to globally emerging resistance....
Citation: Gut Pathogens 2010 2:18 -
Epidemiology of plasmid-mediated quinolone resistance in salmonella enterica serovar typhimurium isolates from food-producing animals in Japan
A total of 225 isolates of Salmonella enterica serovar Typhimurium from food-producing animals collected between 2003 and 2007 were examined for the prevalence of plasmid-mediated quinolone resistance (PMQR) dete...
Citation: Gut Pathogens 2010 2:17 -
Pseudomonas fluorescens alters epithelial permeability and translocates across Caco-2/TC7 intestinal cells
Pseudomonas fluorescens has long been considered as a psychrotrophic microorganism. Recently, we have shown that clinical strains of P. fluorescens (biovar 1) are able to adapt at a growth temperature of 37°C or ...
Citation: Gut Pathogens 2010 2:16 -
PFGE, Lior serotype, and antimicrobial resistance patterns among Campylobacter jejuni isolated from travelers and US military personnel with acute diarrhea in Thailand, 1998-2003
Campylobacter jejuni is a major cause of gastroenteritis worldwide. In Thailand, several strains of C. jejuni have been isolated and identified as major diarrheal pathogens among adult travelers. To study the epi...
Citation: Gut Pathogens 2010 2:15 -
Campylobacter jejuni induces transcytosis of commensal bacteria across the intestinal epithelium through M-like cells
Recent epidemiological analyses have implicated acute Campylobacter enteritis as a factor that may incite or exacerbate inflammatory bowel disease (IBD) in susceptible individuals. We have demonstrated previously...
Citation: Gut Pathogens 2010 2:14 -
Systematic review and meta-analysis: the relationship between the Helicobacter pylori dupA gene and clinical outcomes
In 2005, the first disease-specific Helicobacter pylori virulence factor that induced duodenal ulcer and had a suppressive action on gastric cancer has been identified, and was named duodenal ulcer promoting gene...
Citation: Gut Pathogens 2010 2:13 -
Trend of Entamoeba histolytica infestation in Kolkata
Entamoeba histolytica infection is found almost all over the world and is highly endemic and a major cause of parasitic diarrhoea particularly in the developing countries.
Citation: Gut Pathogens 2010 2:12 -
Isolation and detection of Mycobacterium avium subsp. paratuberculosis (MAP) from cattle in Ireland using both traditional culture and molecular based methods
Mycobacterium avium subsp. paratuberculosis (MAP) causes a chronic gastroenteritis affecting many species. Johne's disease is one of the most widespread and economically important disease of ruminants. Since 1992...
Citation: Gut Pathogens 2010 2:11 -
Are probiotics a feasible intervention for prevention of diarrhoea in the developing world?
With more than 1.4 million of the 9 million child deaths being attributed to diarrhoea in 2008 and 49% of them occurring in five countries namely, India, Nigeria, Democratic Republic of the Congo, Pakistan and...
Citation: Gut Pathogens 2010 2:10 -
Serum neopterin is elevated in patients infected with Shigella
Neopterin is produced by human macrophages/monocytes when stimulated with interferon-gamma. Production of neopterin is found in serum, cerebrospinal fluid (CSF) and urine of patients with infections by viruses...
Citation: Gut Pathogens 2010 2:9 -
Enteropathogenic Escherichia coli, Samonella, Shigella and Yersinia: cellular aspects of host-bacteria interactions in enteric diseases
A successful infection of the human intestine by enteropathogenic bacteria depends on the ability of bacteria to attach and colonize the intestinal epithelium and, in some cases, to invade the host cell, survi...
Citation: Gut Pathogens 2010 2:8 -
Shiga toxin producing Escherichia coli: identification of non-O157:H7-Super-Shedding cows and related risk factors
Shiga toxin producing Escherichia coli (STEC) are an important cause of human gastro-enteritis and extraintestinal sequelae, with ruminants, especially cattle, as the major source of infection and reservoir. In t...
Citation: Gut Pathogens 2010 2:7 -
Genetic affinities of Helicobacter pylori isolates from ethnic Arabs in Kuwait
Helicobacter pylori is one of the most genetically diverse of bacterial species, and since the 5'-end of cagA gene and the middle allele of vacA gene of H. pylori from different populations exhibit considerable p...
Citation: Gut Pathogens 2010 2:6 -
Probiotic therapy - recruiting old friends to fight new foes
Against a backdrop of increasing antibiotic resistance, and the emergence of new and evolving pathogens, clinicians are increasingly forced to consider alternative therapies - probiotics are one such alternative.
Citation: Gut Pathogens 2010 2:5 -
Emerging trends in the etiology of enteric pathogens as evidenced from an active surveillance of hospitalized diarrhoeal patients in Kolkata, India
This study was conducted to determine the etiology of diarrhoea in a hospital setting in Kolkata. Active surveillance was conducted for 2 years on two random days per week by enrolling every fifth diarrhoeal p...
Citation: Gut Pathogens 2010 2:4 -
Current insights in to the pathophysiology of Irritable Bowel Syndrome
Irritable Bowel Syndrome (IBS) represents a functional disorder of gastrointestinal tract without the presence of an anatomic defect, in which abdominal pain is relieved with defecation and is associated with ...
Citation: Gut Pathogens 2010 2:3 -
Helicobacter pylori: a poor man's gut pathogen?
Helicobacter pylori is one of the human pathogens with highest prevalence around the world; yet, its principal mode of transmission remains largely unknown. The role of H. pylori in gastric disease and cancer has...
Citation: Gut Pathogens 2010 2:2 -
Mycobacterium avium subsp. paratuberculosis as a trigger of type-1 diabetes: destination Sardinia, or beyond?
Type 1 diabetes mellitus (T1DM) is a multifactorial autoimmune disease in which the insulin producing β cell population is destroyed by the infiltrated T lymphocytes. Even though the exact cause of T1DM is yet...
Citation: Gut Pathogens 2010 2:1 -
A rhodanine agent active against non-replicating intracellular Mycobacterium avium subspecies paratuberculosis
Antibiotic therapy targeting chronic mycobacterial disease is often ineffective due to problems with the emergence of drug resistance and non-replicating persistent intracellular antibiotic resistant phenotype...
Citation: Gut Pathogens 2009 1:25 -
Helicobacter pylori - a seasoned pathogen by any other name
Helicobacter pylori is a well known inhabitant of human stomach which is linked to peptic ulcer disease and gastric adenocarcinoma. It was recently shown in several studies that H. pylori can be harnessed as a su...
Citation: Gut Pathogens 2009 1:24 -
Penicillin-binding Proteins (PBP) and Lmo0441 (a PBP-like protein) play a role in Beta-lactam sensitivity of Listeria monocytogenes
While seven penicillin-binding proteins (PBPs) or PBP-like proteins have been identified either by radiolabelled penicillin binding studies or genomic analysis, only PBP3 has been considered of interest for Be...
Citation: Gut Pathogens 2009 1:23 -
Adhesive threads of extraintestinal pathogenic Escherichia coli
The ability to adhere to host surfaces is by far the most vital step in the successful colonization by microbial pathogens. Colonization begins with the attachment of the bacterium to receptors expressed by ce...
Citation: Gut Pathogens 2009 1:22 -
A hundred-year-old insight into the gut microbiome!
As the National Institutes of Health-funded Human Microbiome Project enters its second phase, and as a major part of this project focuses on the human gut microbiome and its effects on human health, it might h...
Citation: Gut Pathogens 2009 1:21 -
Blood profile holds clues to role of infection in a premonitory state for idiopathic parkinsonism and of gastrointestinal infection in established disease
The two-stage neuroinflammatory process, containment and progression, proposed to underlie neurodegeneration may predicate on systemic inflammation arising from the gastrointestinal tract. Helicobacter infection ...
Citation: Gut Pathogens 2009 1:20 -
Probiotics and gastrointestinal disease: successes, problems and future prospects
Gastrointestinal disease is a major cause of morbidity and mortality worldwide each year. Treatment of chronic inflammatory gastrointestinal conditions such as ulcerative colitis and Crohn's disease is difficu...
Citation: Gut Pathogens 2009 1:19 -
Antimicrobial resistances do not affect colonization parameters of intestinal E. coli in a small piglet group
Although antimicrobial resistance and persistence of resistant bacteria in humans and animals are major health concerns worldwide, the impact of antimicrobial resistance on bacterial intestinal colonization in...
Citation: Gut Pathogens 2009 1:18 -
Possible transmission of Mycobacterium avium subspecies paratuberculosis through potable water: lessons from an urban cluster of Crohn's disease
A "cluster" of patients refers to the geographic proximity of unrelated patients with the same disease and suggests a common environmental cause for that disease. Clusters of patients with Crohn's disease have...
Citation: Gut Pathogens 2009 1:17 -
The case for biocentric microbiology
Microbiology is a relatively modern scientific discipline intended to objectively study microorganisms, including pathogens and nonpathogens. However, since its birth, this science has been negatively affected...
Citation: Gut Pathogens 2009 1:16 -
Mycobacterium avium subspecies paratuberculosis, Crohn's disease and the Doomsday scenario
Johne's disease is chronic inflammation of the intestine caused by Mycobacterium avium subspecies paratuberculosis. Infection and disease are mainly in domestic livestock but can affect many species including pri...
Citation: Gut Pathogens 2009 1:15 -
Salmonella enterica serovar Typhimurium adhesion and cytotoxicity during epithelial cell stress is reduced by Lactobacillus rhamnosus GG
Physiological stressors may alter susceptibility of the host intestinal epithelium to infection by enteric pathogens. In the current study, cytotoxic effect, adhesion and invasion of Salmonella enterica serovar T...
Citation: Gut Pathogens 2009 1:14 -
Characterisation of Campylobacter jejuni genes potentially involved in phosphonate degradation
Potential biological roles of the Campylobacter jejuni genes cj0641, cj0774c and cj1663 were investigated. The proteins encoded by these genes showed sequence similarities to the phosphonate utilisation PhnH, K a...
Citation: Gut Pathogens 2009 1:13 -
Disease association with two Helicobacter pylori duplicate outer membrane protein genes, homB and homA
homB encodes a Helicobacter pylori outer membrane protein. This gene was previously associated with peptic ulcer disease (PUD) and was shown to induce activation of interleukin-8 secretion in vitro, as well as co...
Citation: Gut Pathogens 2009 1:12 -
Exposure to bile influences biofilm formation by Listeria monocytogenes
In the present study we demonstrate that the initial attachment of Listeria monocytogenes cells to plastic surfaces was significantly increased by growth in the presence of bile. Improved biofilm formation was co...
Citation: Gut Pathogens 2009 1:11 -
Spirochaetes as intestinal pathogens: Lessons from a Brachyspira genome
Anaerobic spirochaetes of the genus Brachyspira have long been known as important gut pathogens of pigs, but increasingly they are recognised as causing disease in birds and other animal species, including human ...
Citation: Gut Pathogens 2009 1:10 -
An oral recombinant Salmonella enterica serovar Typhimurium mutant elicits systemic antigen-specific CD8+ T cell cytokine responses in mice
The induction of antigen-specific CD8+ T cell cytokine responses against an attenuated, oral recombinant Salmonella enterica serovar Typhimurium vaccine expressing a green fluorescent protein (GFP) model antigen ...
Citation: Gut Pathogens 2009 1:9 -
Lactobacillus delbrueckii ssp. bulgaricus B-30892 can inhibit cytotoxic effects and adhesion of pathogenic Clostridium difficile to Caco-2 cells
Probiotic microorganisms are receiving increasing interest for use in the prevention, treatment, or dietary management of certain diseases, including antibiotic-associated diarrhea (AAD). Clostridium difficile is...
Citation: Gut Pathogens 2009 1:8 -
Thinking beyond the colon-small bowel Involvement in clostridium difficile infection
Small intestinal Clostridium difficile seems to be increasing in incidence. The spectrum of Clostridium difficile infection (CDI) has definitely expanded with small bowel involvement. They are more frequently rep...
Citation: Gut Pathogens 2009 1:7 -
A randomized, double-blind, placebo-controlled pilot study of a probiotic in emotional symptoms of chronic fatigue syndrome
Chronic fatigue syndrome (CFS) is complex illness of unknown etiology. Among the broad range of symptoms, many patients report disturbances in the emotional realm, the most frequent of which is anxiety. Resear...
Citation: Gut Pathogens 2009 1:6 -
The prevalence of the duodenal ulcer promoting gene (dupA) in Helicobacter pylori isolates varies by ethnic group and is not universally associated with disease development: a case-control study
The putative H. pylori pathogenicity-associated factor dupA has been associated with IL-8 induction in vitro, and duodenal ulcer (DU) and gastric cancer (GC) development in certain populations, but this associati...
Citation: Gut Pathogens 2009 1:5 -
Monensin causes dose dependent inhibition of Mycobacterium avium subspecies paratuberculosis in radiometric culture
Mycobacterium avium subspecies paratuberculosis (MAP) causes a chronic wasting diarrheal disease in ruminants called Johne's disease, that is evocative of human inflammatory bowel disease (IBD). Agents used to tr...
Citation: Gut Pathogens 2009 1:4 -
Gut pathogens: invaders and turncoats in a complex cosmos
Intestinal infections and diarrhoeal diseases of humans are under-reported yet each account worldwide for more deaths than those from Tuberculosis. For external gut pathogens to do this they have to penetrate,...
Citation: Gut Pathogens 2009 1:3 -
Campylobacter jejuni induces transcellular translocation of commensal bacteria via lipid rafts
Campylobacter enteritis represents a risk factor for the development of inflammatory bowel disease (IBD) via unknown mechanisms. As IBD patients exhibit inflammatory responses to their commensal intestinal microf...
Citation: Gut Pathogens 2009 1:2 -
Gut Pathogens: enteric health at the interface of changing microbiology
Citation: Gut Pathogens 2009 1:1
Follow
- ISSN: 1757-4749 (electronic)