Blood profile holds clues to role of infection in a premonitory state for idiopathic parkinsonism and of gastrointestinal infection in established disease

Table 3 Comparison of percentage distribution of lymphocyte subsets in probands with idiopathic parkinsonism and their spouses with Multitest reference mean.

Subset	Reference mean	Probands		Contrast with reference	Spouses		Contrast with reference
	% subset sum	% below	% above	p-value*	% below	% above	p-value
CD3+	72	42.5	57.5	0.5	28.1	71.9	0.0007
CD4+	45	45.3	54.7	0.09	24.6	75.4	0.0001
CD8+	24	59.4	40.6	0.06	52.6	47.4	0.3
CD19+	13	67.9	32.1	0.0001	64.9	35.1	0.003
CD 16+56+	14	33.0	67.0	0.0001	63.2	36.8	0.2

* Wilcoxon signed-rank test assuming reference mean ≡ median.
For example: in probands, CD3+ subset conformed with reference mean value of 72% and range (see Table 4) of 56-86%, in their spouses with range but not mean.

ISSN: 1757-4749