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Table 2 Effect of sterile media and CFS/CFT from CD-9689 and LDB B-30892 co-culture on Caco-2 cells.

From: Lactobacillus delbrueckii ssp. bulgaricus B-30892 can inhibit cytotoxic effects and adhesion of pathogenic Clostridium difficile to Caco-2 cells

Media only or CFS

Appearance of Caco-2 cells

Dilution

1:2

1:4

1:8

1:16

RCM

N1

N

N

N

CD-9689 CFS (CFT)

C2

C

C

N

MRS

N

N

N

N

LDB B-30892 CFS (LDB-CFS)

N

N

N

N

LDB B-30892 – CD-9689 co-culture CFS

N

N

N

N

Heat-killed LDB B-30892 – CD-9689 co-culture CFS

C

C

C

N

  1. 1 N, normal cellular morphology
  2. 2 C, signs of cytotoxicity (e.g. cell rounding and detachment from the substrate)
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Gut Pathogens

ISSN: 1757-4749