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Figure 3 | Gut Pathogens

Figure 3

From: Pseudomonas fluorescens alters epithelial permeability and translocates across Caco-2/TC7 intestinal cells

Figure 3

Pseudomonas fluorescens MF37, P. fluorescens MFN1032 and P. aeruginosa PAO1 cause disruption of the apical F-actin cytoskeleton. Fluorescent F-actin staining showing organized F-actin filaments lining the apical tight-junction system of control differentiated Caco-2/TC7 cell monolayer (A). In cell monolayers infected with P. fluorescens MF37 (B), P. fluorescens MFN1032 (C) and P. aeruginosa PAO1 (D) the sub-membrane microfilament network is loose. Clusters of amorphous actin can be observed, particularly after infection with P. fluorescens MFN1032 and P. aeruginosa PAO1 (arrows).

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