Skip to main content

Table 1 Bacterial adhesive structures and their cognate receptors

From: Enteropathogenic Escherichia coli, Samonella, Shigella and Yersinia: cellular aspects of host-bacteria interactions in enteric diseases

Pathogen

Adhesin

Receptor

Effect on host cell

Reference

EPEC

BFP

EspA

Intimin

Not fully elucidated

Not fully elucidated

Tir

Activation of T3SS1 and formation of A/E2 lesions and changes of epithelial cell morphology

[2, 4]

Salmonella sp.

FimA

FimH

Mannosylated proteins in epithelial cells

Activation of T3SS and transport of effector proteins necessary for invasion

[14]

Shigella sp.

Complex IpaB/C

IpaB

Integrin α5 β1

CD44 (natural receptor of hyaluronic acid)

Activation of T3SS and transport of effector proteins necessary for invasion

[18, 19]

Yersinia sp.

Invasin

YadA

β1 integrins (natural receptor of fibronectin)

Activation of T3SS and transport of effector proteins necessary for invasion and/or apoptosis

[44]

  1. 1. T3SS: Type III Secretion System.
  2. 2. A/E lesion: attaching/effacing lesion.