Figure 1
The proposed role of the intestinal microflora in the development of obesity in infants *1 Host-derived polysaccharides can be fermented by Bacteroides thetaiotaomicron to predominantly acetate, which is absorbed in the liver leading to de novo triglyceride synthesis [23]. Simultaneously, the FIAF expression by the intestinal epithelium is suppressed by Bacteroides thetaiotaomicron resulting in increased production and storage of triglyceride derived fatty acids from the liver [24]. *2 Staphylococcus as a marker of delayed acquisition of a complex anaerobic microflora [31]. *3 Subgroup of Clostridium cluster XIVa: Roseburia spp and Eubacterium rectale group [28]. *4 Microbial fermentation may release about 10% of extra dietary energy for host cells [30]. TG: Triglyceride PS: Polysaccharides FIAF: Fasting-induced adipose factor OS: Oligosaccharides Double sided white arrow; up and down: mutual competitive bacterial inhibition