Skip to main content
Figure 1 | Gut Pathogens

Figure 1

From: In vitro cytokine profiles and viability of different human cells treated with whole cell lysate of Mycobacterium avium subsp. paratuberculosis

Figure 1

(A) Cytokine analysis of culture supernatants of human peripheral blood mononuclear cells (PBMCs) upon treatment with MAP lysate indicated increased secretion of IL-1β, IL-6, IL-8, IL-10 and TNF-α (B) Cytokine analysis of culture supernatants of AGS cells resulted in increased secretion of IL-8 (C) Cytokine analysis of the culture supernatants of PANC-1 cells resulted in increased secretion of IL-8 in a dose and time dependent manner. The statistical analysis (of untreated fractions and those with the treatment of different concentrations of MAP lysate and LPS) corresponding to PBMCs at 24 and 48 hr and AGS and PANC-1 at 24 hr, 48 hr and 72 hr resulted in p < 0.05 indicating significant increase in the secretion of cytokines.

Back to article page