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Figure 5 | Gut Pathogens

Figure 5

From: Effects of indole on drug resistance and virulence of Salmonella enterica serovar Typhimurium revealed by genome-wide analyses

Figure 5

Proposed regulatory network controlled by indole. Indole induces the multidrug efflux system genes acrAB and tolC through the increased expression of ramA. Indole represses flagellar and SPI-1 genes in a ram locus-independent manner. However, the indole-mediated upregulation of ramA may be partially involved in decreased expression of SPI-1 genes.

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