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Table 3 The distribution of NOD2 genotypes in patients with inflammatory bowel disease (IBD), Crohn’s disease (CD), ulcerative colitis (UC) and in controls (HC) [ n (%)]

From: Lactase persistence, NOD2 status and Mycobacterium avium subsp. paratuberculosis infection associations to Inflammatory Bowel Disease

NOD2 genotype frequency n (%)
Group WT/WT Heterocygotes Homocygotes
IBD ( n= 278)
 R702W 241 (86.7) 34 (12.2) 3 (1.1)
 G908R 273 (98.2) 5 (1.8) 0 (0.0)
 1007 fs 263 (94.6) 15 (5.4) 0 (0.0)
CD ( n= 173)
 R702W 145 (83.8) 26 (15.0) 2 (1.2)
 G908R 168 (97.1) 5 (2.9) 0 (0.0)
 1007 fs 158 (91.3) 15 (8.7)* 0 (0.0)
UC ( n= 105)
 R702W 96 (91.4) 8 (7.6) 1 (1.0)
 G908R 105 (100.0) 0 (0.0) 0 (0.0)
 1007 fs 105 (100.0) 0 (0.0) 0 (0.0)
HC ( n= 188)
 R702W 171 (91.0) 17 (9.0) 0 (0.0)
 G908R 186 (98.9) 2 (1.1) 0 (0.0)
 1007 fs 183 (97.3) 5 (2.7) 0 (0.0)
  1. WT: Wild-type
  2. * 1007 fs allele frequency, CD versus UC (p = 0.021) and CD versus controls (p = 0.0135).