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Table 4 NOD2 and LCT mutation distribution in MAP infected and non-infected individuals among Crohn’s disease (CD), ulcerative colitis (UC) and in control (HC) cohorts [ n (%)]

From: Lactase persistence, NOD2 status and Mycobacterium avium subsp. paratuberculosis infection associations to Inflammatory Bowel Disease

Number of mutations

CD (n = 173)

UC (n = 105)

HC (n = 188)

 

MAP +

MAP -

MAP +

MAP -

MAP +

MAP -

NOD2

0

29 (16.76)

103 (59.54)

19 (18.10)

77 (40.96)

77 (40.96)

87 (46.28)

1

7 (4.05)

26 (15.03)

1 (0.95)

7 (6.67)

8 (4.26)

16 (8.51)

2

1 (0.58)

7 (4.05)

0 (0.00)

1 (0.95)

0 (0.0)

0 (0.00)

LCT

0

27 (15.61)

109 (63.01)

14 (13.33)

64 (60.95)

73 (38.83)

80 (42.55)

1

10 (5.78)

27 (15.61)

6 (5.71)

21 (20.00)

12 (6.38)

23 (12.23)

  1. No significant differences were detected among groups except for CD versus HC NOD2 0 and CD versus HC LCT 0 (p < 0.0001).