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Table 6 Multivariate logistic regression analysis of risk factors for subjects with inflammatory bowel disease (IBD), Crohn’s disease (CD) or Ulcerative Colitis (UC) versus those of healthy controls

From: Lactase persistence, NOD2 status and Mycobacterium avium subsp. paratuberculosis infection associations to Inflammatory Bowel Disease

 

Odds ratio (95% CI)

P

CD (n = 173)

C allele carrier in LCT

1.44 (0.93-2.24)

0.1

MAP (PCR positive vs PCR negative)

0.33 (0.21-0.53)

<0.0001

NOD-2 mutant

2.05 (1.18-3.58)

0.011

UC (n = 105)

C allele carrier in LCT

2.16 (1.25-3.71)

0.005

MAP (PCR positive vs PCR negative)

0.29 (0.16-0.50)

<0.0001

NOD-2 mutant

0.67 (0.30-1.51)

0.338

IBD (n = 278)

C allele carrier in LCT

1.65 (1.11-2.45)

0.013

MAP (PCR positive vs PCR negative)

0.31 (0.21-0.47)

<0.0001

NOD-2 mutant

1.74 (1.00-3.01)

0.046

  1. In this analysis C allele carrier and MAP presence were treated as categorical values. Significance was considered when P < 0.05.