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Table 6 Multivariate logistic regression analysis of risk factors for subjects with inflammatory bowel disease (IBD), Crohn’s disease (CD) or Ulcerative Colitis (UC) versus those of healthy controls

From: Lactase persistence, NOD2 status and Mycobacterium avium subsp. paratuberculosis infection associations to Inflammatory Bowel Disease

  Odds ratio (95% CI) P
CD (n = 173)
C allele carrier in LCT 1.44 (0.93-2.24) 0.1
MAP (PCR positive vs PCR negative) 0.33 (0.21-0.53) <0.0001
NOD-2 mutant 2.05 (1.18-3.58) 0.011
UC (n = 105)
C allele carrier in LCT 2.16 (1.25-3.71) 0.005
MAP (PCR positive vs PCR negative) 0.29 (0.16-0.50) <0.0001
NOD-2 mutant 0.67 (0.30-1.51) 0.338
IBD (n = 278)
C allele carrier in LCT 1.65 (1.11-2.45) 0.013
MAP (PCR positive vs PCR negative) 0.31 (0.21-0.47) <0.0001
NOD-2 mutant 1.74 (1.00-3.01) 0.046
  1. In this analysis C allele carrier and MAP presence were treated as categorical values. Significance was considered when P < 0.05.