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Table 2 Serological responses to H. pylori antigens in initial and follow-up sera from Cohort 1 Rhesus macaques in relation to initial H. pylori status

From: Serologic host response to Helicobacter pylori and Campylobacter jejuni in socially housed Rhesus macaques (Macaca mulatta)

   

% positive

   

H. pylori

CagA

Timing

Status

Number of specimens

IgG

IgAc

IgGd

Initial

+a

17

100

88

82

 

-

13

30

23

23

Follow-up

+b

28

93

61

61

 

-

12

0

18

0

  1. a Positive (colonized) defined as detection of H. pylori from culture or histological examination of gastric antral biopsy.
  2. b Positive (colonized) defined as detection of H. pylori from culture or histological examination of gastric antral biopsy, or presence of IgG ODR (>0.34) in the initial specimen. A total of 40 follow-up serum specimens were available for examination.
  3. c Positive was defined as ODR >0.4; based on Mean + 2 intervals of SD of values from reference group of uninfected monkeys.
  4. d Positive was defined as ODR >0.2; based on Mean + 2 intervals of SD of values from reference group of uninfected monkeys.
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Gut Pathogens

ISSN: 1757-4749