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Table 2 Serological responses to H. pylori antigens in initial and follow-up sera from Cohort 1 Rhesus macaques in relation to initial H. pylori status

From: Serologic host response to Helicobacter pylori and Campylobacter jejuni in socially housed Rhesus macaques (Macaca mulatta)

    % positive
    H. pylori CagA
Timing Status Number of specimens IgG IgAc IgGd
Initial +a 17 100 88 82
  - 13 30 23 23
Follow-up +b 28 93 61 61
  - 12 0 18 0
  1. a Positive (colonized) defined as detection of H. pylori from culture or histological examination of gastric antral biopsy.
  2. b Positive (colonized) defined as detection of H. pylori from culture or histological examination of gastric antral biopsy, or presence of IgG ODR (>0.34) in the initial specimen. A total of 40 follow-up serum specimens were available for examination.
  3. c Positive was defined as ODR >0.4; based on Mean + 2 intervals of SD of values from reference group of uninfected monkeys.
  4. d Positive was defined as ODR >0.2; based on Mean + 2 intervals of SD of values from reference group of uninfected monkeys.