Figure 1
From: Emerging importance of holobionts in evolution and in probiotics
The concept of hologenome. Hologenome consist of genome of holobiont which includes host and its associated symbiota having a mutual beneficial relationship. Symbiota not only protects the host from pathogens but also decreases immune disorders by immunomodulation. While host provides shelter and nutrients to the symbiota, symbiota in turn also improve various body functions such as digestion to provide essential nutrients to the host.