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Table 1 BLAST analysis between MAP Hsp65, Mtb Hsp65 and GAD65 peptide sequences

From: Exploring the role of Mycobacterium avium subspecies paratuberculosis in the pathogenesis of type 1 diabetes mellitus: a pilot study

Proteina

Amino acid region

Amino acid sequence

Amino acid sequence

GAD65

520-535

EERMSRLSKVAPVIKA

 
  

+ER + ++L+ VIKA

75%

MAP Hsp65

364-379

QERLAKLAGGVAVIKA

 
  

QERLAKLAGGVAVIKA

100%

Mtb Hsp65

364-379

QERLAKLAGGVAVIKA

 
  1. a: Sequence identity between MAP Hsp65 and Mtb Hsp65 is 100% within this 16 amino acid region and 75% between GAD65 and both mycobacterial protein.
  2. Abbreviations: GAD65 Glutamic Acid Decarboxylase, MAP Mycobacterium avium subspecies paratuberculosis, Mtb Mycobacterium tuberculosis, Hsp65 Heat shock protein of 65 kDa.