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Figure 1 | Gut Pathogens

Figure 1

From: The neurotoxic effect of clindamycin - induced gut bacterial imbalance and orally administered propionic acid on DNA damage assessed by the comet assay: protective potency of carnosine and carnitine

Figure 1

DNA damage induced in hamster brains (cortex and medulla) by PA or clindamycin-induced bacterial overgrowth together with the protective effects of carnosine and L-carnitine. Neurotoxic effects of PA, bacterial overgrowth and ameliorating effects of both the supplements could be seen as significant changes in tail length (μm) and tail moments (Arbitrary units) (A &B respectively) and percentage changes in both (C &D). All figures are presented as mean±SE bars in the 8 studied groups compared to a control group. It is clear that orally administered PA was more neurotoxic than induced bacterial overgrowth. Carnosine was more protective than carnitine.

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