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Figure 5 | Gut Pathogens

Figure 5

From: The impact of serine protease HtrA in apoptosis, intestinal immune responses and extra-intestinal histopathology during Campylobacter jejuni infection of infant mice

Figure 5

Colonic matrixmetalloproteinase-2 expression following C. jejuni infection of infant mice. Immediately after weaning, infant mice were perorally infected with C. jejuni NCTC11168 (WT, closed circles) or the mutant strain NCTC11168∆htrA (∆htrA, open circles). Uninfected animals (Naïve; open diamonds) served as negative controls. (A) MMP-2 and (B) TIMP-1 mRNA expression levels were determined in colonic ex vivo biopsies taken at day 7 p.i. by quantitative real-time PCR. Numbers of analyzed animals are given in parentheses. Means (black bars) and levels of significance (P-values) determined by the Mann–Whitney-U test are indicated. Data shown were pooled from three independent experiments.

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