Figure 2From: Whole-genome sequencing of clarithromycin resistant Helicobacter pylori characterizes unidentified variants of multidrug resistant efflux pump genesA2146G and A2147G mutations in the 23S rRNA gene identified by illumina sequencing. The aligned results of sequencing reads of two CLR-resistant H. pylori strains (S17 and S26) are shown. Along the top, reference nucleotide sequences of NC_000915 (ATCC26695), and consensus nucleotide sequences of each CLR-resistant strain are shown (black). The lower portion of the sequence viewer shows mapped sequencing reads (yellow and blue). In 479 reads from S17 strain (left), reference nucleotide A was changed to G at position 2146 in 23S rRNA (bold faces). Similarly, reference nucleotide A was changed to G at position 2147 in 23S rRNA in 485 reads from S26 (right).Back to article page