Table 5 SNVs of multidrug resistant efflux pump genes and MICs of CLR

From: Whole-genome sequencing of clarithromycin resistant Helicobacter pylori characterizes unidentified variants of multidrug resistant efflux pump genes

Strain	MICs of CLR (μg/ml)	*hp0605 (hefA )*	*hp0606 (hefB )*	*hp0607 (hefC )*	*hp0969 (hefF )*	*hp0970 (hefE )*	*hp097* 1 *(hefD )*	*hp1327 (hefG )*	*hp1328 (hefH )*	*hp1329 (hefI )*	*hp1487*	*hp1488*	*hp1489*	Total
CLR-susceptible
177	-	0	0	0	0	0	0	0	0	0	0	0	0	0
179	-	29	12	70	51	13	3	22	16	47	30	26	31	350
189	-	0	0	0	0	0	0	0	0	0	0	0	0	0
F32	-	48	20	76	83	24	27	0	0	0	0	0	0	278
F44	-	0	0	0	0	0	0	0	0	0	0	0	0	0
F65	-	0	0	0	0	0	0	0	0	0	0	0	0	0
F79	-	39	15	49	55	16	30	0	0	0	0	0	0	204
CLR-resistant
S1	32	32	17	51	55	9	25	23	18	61	23	13	27	354
S2	32	50	18	74	0	0	0	0	0	0	0	0	0	142
S4	32	39	18	67	55	16	26	0	0	0	0	0	0	221
S8	4	44	19	67	0	0	0	0	0	0	0	0	0	130
S13	16	52	21	80	76	22	31	0	0	0	0	0	0	282
S16	16	54	23	81	0	0	0	0	0	0	0	0	0	158
S17	32	48	19	87	0	0	0	0	0	0	0	0	0	154
S22	64	46	16	69	0	0	0	0	0	0	0	0	0	131
S23	16	1	16	21	14	2	8	38	10	71	23	19	42	265
S26	32	55	24	83	0	0	0	0	0	0	0	0	0	162
174	-	40	11	55	58	19	34	26	10	52	27	19	47	398
194	-	25	7	34	48	15	18	0	0	0	0	0	0	147
Statistics
P value		0.011	0.017	0.038	NS	NS	NS	NS	NS	NS	NS	NS	NS	NS
95% CI		6.1-41.7	2.5-18.8	2.5-69.9

NS; not significant.

Back to article page

ISSN: 1757-4749

Contact us

Submission enquiries: journalsubmissions@springernature.com