Skip to main content

Table 5 SNVs of multidrug resistant efflux pump genes and MICs of CLR

From: Whole-genome sequencing of clarithromycin resistant Helicobacter pylori characterizes unidentified variants of multidrug resistant efflux pump genes

Strain MICs of CLR (μg/ml) hp0605 (hefA ) hp0606 (hefB ) hp0607 (hefC ) hp0969 (hefF ) hp0970 (hefE ) hp097 1 (hefD ) hp1327 (hefG ) hp1328 (hefH ) hp1329 (hefI ) hp1487 hp1488 hp1489 Total
CLR-susceptible
177 - 0 0 0 0 0 0 0 0 0 0 0 0 0
179 - 29 12 70 51 13 3 22 16 47 30 26 31 350
189 - 0 0 0 0 0 0 0 0 0 0 0 0 0
F32 - 48 20 76 83 24 27 0 0 0 0 0 0 278
F44 - 0 0 0 0 0 0 0 0 0 0 0 0 0
F65 - 0 0 0 0 0 0 0 0 0 0 0 0 0
F79 - 39 15 49 55 16 30 0 0 0 0 0 0 204
CLR-resistant
S1 32 32 17 51 55 9 25 23 18 61 23 13 27 354
S2 32 50 18 74 0 0 0 0 0 0 0 0 0 142
S4 32 39 18 67 55 16 26 0 0 0 0 0 0 221
S8 4 44 19 67 0 0 0 0 0 0 0 0 0 130
S13 16 52 21 80 76 22 31 0 0 0 0 0 0 282
S16 16 54 23 81 0 0 0 0 0 0 0 0 0 158
S17 32 48 19 87 0 0 0 0 0 0 0 0 0 154
S22 64 46 16 69 0 0 0 0 0 0 0 0 0 131
S23 16 1 16 21 14 2 8 38 10 71 23 19 42 265
S26 32 55 24 83 0 0 0 0 0 0 0 0 0 162
174 - 40 11 55 58 19 34 26 10 52 27 19 47 398
194 - 25 7 34 48 15 18 0 0 0 0 0 0 147
Statistics
P value   0.011 0.017 0.038 NS NS NS NS NS NS NS NS NS NS
95% CI   6.1-41.7 2.5-18.8 2.5-69.9           
  1. NS; not significant.