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Table 1 Summary of T-cell subsets derived from naïve CD4+ T-cells [295]

From: Animal models to study acute and chronic intestinal inflammation in mammals

T-cell subset Activation factor Transcription factor Cytokines produced
Tfh STAT3 Bcl6 IL-21
Th1 STAT4 T-bet IFN-γ
Th2 STAT6 Gata3 IL-4, IL-13
Th17 STAT3 Rorγt IL-17A, IL-17F
Treg STAT5 Foxp3 IL-10, IL-35, TGF-β