Comparison of a novel chemiluminescent based algorithm to three algorithmic approaches for the laboratory diagnosis of Clostridium difficile infection

Table 2 Turnaround time and reagent costs to detect Clostridium difficile infection in the laboratory

		Stool extraction	Labor time (min)	Turnaround time of test (min)	Apparatus	Individual or series test	Algorithm cost ratio relative to DiaSorin algorithm (%)
DiaSorin	GDH	Yes	15	45	Liaison random access	Both	100
DiaSorin	Toxins A and B	Yes^a	0^a	45	Liaison random access	Both	100
Meridian	ImmunoCard^® GDH	No	5	30	No	Individual	90
Meridian	illumigene ^®	No	15	45	illumipro^®	Individual	90
Alere	C. DIFF Quik Chek GDH^®	No	5	30	No	Individual	50
Alere	TOX A/B Quik Chek^®	No	5	30	No	Individual	50

The cost of each algorithm was evaluated in comparison to the DiaSorin algorithm whose the global costs represent 100 %
^aThe DiaSorin LIAISON^® apparatus is configured in order to automatically perform the toxin assay in case of a positive GDH result (reflex testing). These two assays were performed on the same stool extract

ISSN: 1757-4749