Fig. 2

Macro- and microscopic evaluation of DSS induced colitis, as measured by a clinical colitis score, b colonic MPO activity, and c histological analysis of the mucosal damage of the colon descendens. The values are expressed as mean (bar) value ± standard deviation (whisker). Each bar represents 4– mice and histology (paraffin-embedded sections stained with haematoxylin and eosin) is from one mouse showing changes typical for each group. The numbers represent histological grade and the black bar is 100 µm. *p ≤ 0.05 vs. non-treated littermates; ^†p ≤ 0.05, vs. healthy GF mice; ^#p ≤ 0.05, vs. DSS-treated GF mice; ^‡p ≤ 0.05, vs. DSS-treated CV mice; F1/3/4 1st/3rd/4th filial generation, DSS dextran-sodium sulfate