Fig. 2

Triple positive strains and even the babA2 positive only strains enhance IL-8 production in AGS cells. In vitro IL-8 production from AGS cells co-cultured with randomly selected a triple positive and cagA ⁺/vacA ⁺/babA2 ⁻ strains, and b cagA ⁻/vacA ⁻/babA2 ⁺ and triple negative H. pylori strains (MOI is 100) for 8 h. IL-8 from culture supernatant was measured using ELISA as described in “Methods”. Data are expressed as mean ± standard error of mean (SEM) of 3 experiments in duplicates. *P < 0.05 as compared between groups