Fig. 5

Wild type H. pylori strains cause more apoptotic cell death than their isogenic mutant of babA2 in AGS cells. Apoptosis of AGS cells (i worked as controls) co-cultured with different genotypic variant i.e. ii wild type I-121 strain; and iii isogenic babA2 mutant of I-121 strain for 24 h (MOI is 100), stained with propidium iodide and analysed by flow cytometry. i–iii is only representative profile of at least three experiments carried out with I-121 strain and its babA2 mutant. iv Graphical representation of percentage of apoptotic cells (sub G0 phase) infected with two wild type and their babA2 mutant strains were expressed as mean ± SEM. Wild type is denoted with black filled bar (◼) and mutants denoted with empty bar (◻). *P < 0.05 as compared between groups