Skip to main content
Fig. 3 | Gut Pathogens

Fig. 3

From: De Novo sphingolipid synthesis is essential for Salmonella-induced autophagy and human beta-defensin 2 expression in intestinal epithelial cells

Fig. 3

Effect of myriocin on the membrane recruitment of NOD2 and Atg16L1 in Salmonella-infected SW480 cells. SW480 cells were untreated (CON) or treated with myriocin and then infected by S. typhimurium wild-type strain SL1344. Immunoblots were performed on membrane lysates with antibody to detect Atg16L1 and NOD2expression, and E-cadherin for normalization of membrane protein. Representative immunoblots (a) and densitometric quantification of immunoreactive bands are shown. The relative band intensities of Atg16L1 (b) and NOD2 (c) in untreated (gray) and treated (black) SW480 cells were quantified as fold increases compared with the control cells. Each value represents the mean ± S.E.M. of 3 independent experiments. An asterisk indicates a significant difference (p < 0.05)

Back to article page

Gut Pathogens

ISSN: 1757-4749