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Fig. 2 | Gut Pathogens

Fig. 2

From: The efficacy of thuricin CD, tigecycline, vancomycin, teicoplanin, rifampicin and nitazoxanide, independently and in paired combinations against Clostridium difficile biofilms and planktonic cells

Fig. 2

Activity of antimicrobials independently, and in combination with thuricin CD, against C. difficile DPC6350 biofilms. Effects of various antimicrobials on the viability of C. difficile DPC6350 biofilms, using the XTT-menadione viability assay assessed by measuring OD492 values. Antimicrobials were used at 4x and 2x MIC as well as combinations of 2x MIC thuricin CD with each of the antibiotics at 2x MIC. Asterisks indicate statistically significant reductions in biofilm viabilty relative to the untreated control, determined using the Student’s t test; *P < 0.05, **P < 0.01, ***P < 0.001. TCD thuricin CD, Van vancomycin, Rif rifampicin, Teico teicoplanin, Tig tigecycline, Nit nitazoxanide

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