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Table 1 Minimum inhibitory concentration (MIC) values of antimicrobials against C. difficile strains

From: The efficacy of thuricin CD, tigecycline, vancomycin, teicoplanin, rifampicin and nitazoxanide, independently and in paired combinations against Clostridium difficile biofilms and planktonic cells

Antimicrobial/Strain Teicoplanin nM (μg/ml) Tigecycline nM (μg/ml) Nitazoxanide nM (μg/ml) Rifampicin nM (μg/ml) Thuricin CDa nM (μg/ml) Vancomycinb nM (μg/ml)
20291 R027 78 (0.146) 312 (0.183) 1560 (0.479) 8 (0.0064) 125 (0.703) 625 (0.928)
Liv022 R106 156 (0.292) 625 (0.366) 780 (0.239) 2 (0.0016) 250 (1.406) 1250 (1.856)
TL178 R002 156 (0.292) 625 (0.366) 390 (0.120) 2 (0.0016) 500 (2.812) 625 (0.928)
DPC6350 156 (0.292) 156 (0.091) 1560 (0.479) 2 (0.0016) 125 (0.703) 625 (0.928)
VPI10463 78 (0.146) 156 (0.091) 780 (0.239) 2 (0.0016) 125 (0.703) 312 (0.464)
  1. MICs of various antimicrobials against planktonic cells of C. difficile strains expressed in nanomolar concentrations and also in μg/ml in parentheses and in italics
  2. The MICs of thuricin CDa and vancomycinb against strains 20291 R027, Liv022 R106 and TL178 R002 were already determined and reported in our previous study [7]