Fig. 1

Intestinal C. jejuni colonization in mice lacking IL-23p19, IL-22 or IL-18. Conventional a wildtype, b IL-23p19^−/−, c IL-22^−/− and d IL-18^−/− mice were perorally infected with C. jejuni strain ATCC 43431 by gavage at days 0, 1 and 2. Pathogenic loads were determined in fecal samples (CFU colony forming units per gram) at distinct time points (d day) postinfection (p.i.) as indicated by culture. Numbers of mice harboring C. jejuni out of the total number of analyzed animals are given in parentheses. Medians (black bars) and levels of significance (p values) determined by Mann–Whitney U test are indicated. Data were pooled from three independent experiments