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Fig. 8 | Gut Pathogens

Fig. 8

From: The IL-23/IL-22/IL-18 axis in murine Campylobacter jejuni infection

Fig. 8

IL-23p19, IL-22, and IL-18 mRNA in colonic ex vivo biopsies derived from C. jejuni infected mice lacking IL-23p19, IL-22 or IL-18. Conventional wildtype (WT), IL-23p19−/−, IL-22−/− and IL-18−/− mice were perorally infected with C. jejuni strain ATCC 43431 by gavage at days 0, 1 and 2. a IL-23 p19, b IL-22, and c IL-18 mRNA expression levels were determined in colonic ex vivo biopsies at day (d) 14 postinfection (black circles) by Real Time PCR and expressed in Arbitrary Units (fold expression). Naive (N) mice served as uninfected controls (white circles). Medians (black bars), levels of significance (p values) determined by Mann–Whitney U test, and numbers of analyzed animals (in parentheses) are indicated. Data were pooled from three independent experiments

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