Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 2 Antimicrobila resistance genes of KP617 and the reference strains

From: Comparative genomic analysis of Klebsiella pneumoniae subsp. pneumoniae KP617 and PittNDM01, NUHL24835, and ATCC BAA-2146 reveals unique evolutionary history of this strain

Antibiotics Resistance gene % identity Query/HSP length Predicted phenotype Accession number Positiona
KP617 PittNDM01 BAA-2146 NHUL24385
Aminoglycosides aacA4 100 555/555 Aminoglycoside resistance KM278199    P3_115183..115737  
aac(3)-IIa 99.77 861/861 X51534    P2_41114..41974  
aac(3)-IId 99.88 861/861 EU022314   P3_64003..64863   
aac(6′)-Ib 100 606/606 M21682   P3_2456..3061 P2_82742..83347  
aadA1 100 789/789 JQ480156   P3_3131..3919   
99.75 792/798 JQ414041   P3_44412..45203   
aadA2 100 792/792 JQ364967 P1_261911..262702 P1_271654..272445   P1_53050..53841
100 780/780 X68227    C_2297697..2298476  
aph(3′)-VIa 98.46 780/780 X07753 P1_4558..5337 P1_4558..5337   
armA 100 774/774 AY220558 P1_267391..268164 P1_277134..277907   
rmtC 100   AB194779    P3_120100..120945  
strA 99.88 804/804 AF321551   P3_29207..30010   
100    P2_53242..54045  
strB 99.88 837/837 M96392   P3_30010..30846   
100    P2_52406..53242  
aac(6′)Ib-cr 100 600/600 Fluoroquinolone and aminoglycoside resistance DQ303918 C_612688..613287 C_1122863..1123462   
  P1_136163..136762 P2_38111..38710  
Beta-lactams blaOXA-1 100 831/831 Beta-lactam resistance J02967 C_613418..614248 C_1121902..1122732   
  P1_136893..137723 P2_38841..39671  
blaOXA-9 100 840/840 JF703130   P3_3964..4803   
blaOXA-232 100 798/798 JX423831 P2_3878..4675 P4_3878..4675   
blaNDM-1 100 813/813 FN396876 P1_7770..8582 P1_7770..8582 P3_122191..123003  
blaNDM-5 100 813/813 JN104597     P2_10716..11528
blaCTX-M-15 100 876/876 DQ302097    C_5407907..5408782  
  P3_68389..69264 P2_47128..48003 P1_47694..48569
blaTEM-1A 100 861/861 HM749966   P3_5503..6363   
blaTEM-1B 100 861/861 JF910132    P2_50825..51685  
595/861     P1_49351..49945
blaSHV-11 100 861/861 GQ407109   P3_57446..58306 C_2612965..2613825  
99.88    P2_36311..37171  
blaSHV-28 100 861/861 HM751101     C_1087615..1088475
99.88 C_1078475..1079335 C_656815..657675   
blaCMY-6 100 1146/1146 AJ011293    P3_72203..73348  
Fluoroquinolones aac(6′)Ib-cr 100 600/600 Fluoroquinolone and aminoglycoside resistance DQ303918 C_612688..613287 C_1122863..1123462   
  P1_136163..136762 P2_38111..38710  
99.42 519/519 EF636461   P3_2543..3061 P2_82742..83260  
99.61    P3_115219..115737  
QnrB1 99.85 682/681 Quinolone resistance EF682133 P1_130519..131200 P1_130247..130928   
QnrB58 98.68 681/681 JX259319    P2_26062..26742  
oqxA 100 1176/1176 EU370913    C_4169699..4170874  
99.23 C_4847144..4848319 C_4793024..4794199   C_4849531..4850706
oqxB 98.83 3153/3153 EU370913 C_4843968..4847120 C_4789848..4793000 C_4170898..4174050  
98.79     C_4846355..4849507
Fosfomycin fosA 97.38 420/420 Fosfomycin resistance NZ_AFBO01000747 C_2957629..2958048 C_2903507..2903926   C_2946180..2946599
97.14    C_667959..668378  
MLS—macrolide, lincosamide and streptogramin B ere(A) 95.11 1227/1227 Macrolide resistance AF099140   P3_45289..46515   
mph(A) 100 906/906 D16251    P1_16503..17408  
mph(E) 99.89 885/885 EU294228 P1_271994..272878 P1_281737..282621   
msr(E) 100 1476/1476 Macrolide, Lincosamide and Streptogramin B resistance EU294228 P1_270463..271938 P1_280206..281681   
Phenicol catB3 100 442/633 Phenicol resistance AJ009818   P1_137861..138302 P2_39809..40250  
C_614386..614827 C_1121323..1121764   
cmlA1 99.13   AB212941   P3_42931..44190   
Rifampicin ARR-2 100 453/453 Rifampicin resistance HQ141279   P3_46791..47243   
ARR-3    CP002151    C_2298894..2299820  
Sulphonamides sul1 100 927/927 Sulphonamide resistance CP002151 P1_263120..264046 P1_272863..273789 P3_116160..117086  
sul1 100 837/837 JN581942   P3_41559..42395   
sul2 100 816/816 GQ421466   P3_28331..29146   
Tetracyclines tet(A) 100 1200/1200 Tetracycline resistance AJ517790    P1_19168..20367  
Trimethoprim dfrA1 100 474/474 Trimethoprim resistance X00926 C_3627607..3628080 C_3573485..3573958   
dfrA12 100 498/498 AB571791 P1_261006..261503 P1_270749..271246   P1_52145..52642
dfrA14 99.59 483/483 DQ388123   P1_144525..145007 P2_8272..8754  
  1. KP617: C, CP012753.1; P1, CP012754.1; P2, CP012755.1
  2. PittNDM01: C, CP006798.1; P1, CP006799.1; P2, CP006800.1; P3, CP006801.1; P4, CP006802.1
  3. ATCC BAA-2146: C, CP006659.2; P1 (PCuAs), CP006663.1; P2 (PHg), CP006662.2; P3, CP006660.1; P4, CP006661.1
  4. NUHL24385: C, CP014004.1; P1, CP014005.1; P2, CP014006.1
  5. a C chromosome, P plasmid