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Table 1 Clinical characteristics of diabetic and non-diabetic patients with KPLA

From: The emergence of Klebsiella pneumoniae liver abscess in non-diabetic patients and the distribution of capsular types

 

Non-DM

(n = 120)

DM

(n = 110)

p

Age in years

64.1 ± 16.3

63.5 ± 14.6

0.779

Male

69 (57.5)

80 (72.7)

0.016

Charlson score

1.1 ± 1.8

2.4 ± 1.9

<0.001

Underlying disease

 Malignancy

11 (9.2)

10 (9.1)

0.984

 Alcoholism

4 (3.3)

8 (7.3)

0.180

 Chronic kidney disease

4 (3.3)

8 (7.3)

0.180

 Liver cirrhosis

5 (4.2)

1 (0.9)

0.215

 Congestive heart failure

8 (6.7)

5 (4.5)

0.487

 Chronic lung disease

5 (4.2)

5 (4.5)

1.000

 Cerebrovascular accident

11 (9.2)

8 (7.3)

0.602

APACHE II score

12.3 ± 6.9

14.5 ± 7.4

0.018

HbA1c

5.6 ± 1.2

9.2 ± 2.6

<0.001

Capsular type K1 and K2

94 (81.7)a

70 (70.7)b

0.057

Wild-type antibiotic susceptibility

113 (94.2)

103 (93.6)

0.867

Origin

0.749

 Cryptogenic

103 (85.8)

96 (87.3)

 Biliary tract origin

17 (14.2)

14 (12.7)

Abscess location

0.408

 Right lobe

77 (64.2)

79 (71.8)

 

 Left lobe

21 (17.5)

17 (15.5)

 Both lobes

22 (18.3)

14 (12.7)

Abscess size

0.419

 <5 cm

51 (42.5)

41 (37.3)

 ≥5 cm

69 (57.5)

69 (62.7)

Gas-forming abscess

2 (1.7)

18 (16.4)

<0.001

Multiple abscesses

18 (15.0)

15 (13.6)

0.768

Metastatic infection

6 (5.0)

12 (10.9)

0.096

Outcomes

 ICU admission

23 (19.2)

28 (25.5)

0.252

 Hospital days

26.9 ± 16.5

32.3 ± 38.5

0.178

 Mortality

4 (3.4)

4 (3.6)

0.910

  1. Data are presented as mean ± SD or frequency with percentage (%)
  2. a115 isolates were available for genotyping
  3. b99 isolates were available for genotyping