Skip to main content
Fig. 1 | Gut Pathogens

Fig. 1

From: Clostridium difficile colonization and antibiotics response in PolyFermS continuous model mimicking elderly intestinal fermentation

Fig. 1

Experimental design of the two continuous fermentation models. a Model 1 vegetative CD cells of strain DSM 1296 were added to PC on day 1 and growth was observed in PC and TDC during 16 days. b Model 2 CR and TRs were fed with 100% effluent from IR during period A; and with fresh fermentation medium during periods B–F. Addition of CD spores (107 cfu) of strain 1296 or 13307 was performed in TRs as indicated. IR, inoculum reactor; CR, control reactor; TR, test reactor. CRO I, 75 mg L−1 ceftriaxone addition twice daily; CRO II + III, 150 mg L−1 ceftriaxone addition once daily; CD, C. difficile; MTZ, metronidazole; REC, recovery

Back to article page

Gut Pathogens

ISSN: 1757-4749