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Table 1 Resistance profile of 12 ocular E. coli to nine antibiotics by the Kirby–Bauer disc diffusion method and their biofilm forming potential by and the tissue culture plate (TCP) method

From: Global gene expression in Escherichia coli, isolated from the diseased ocular surface of the human eye with a potential to form biofilm

S. no E. coli strain Ocular sample Patient diagnosis Resistance to antibiotics (µg/disc) Biofilm production by TCP method ±
1 L-1339/2013 Conjunctival swab Conjunctivitis Ce, Cef, Ci, Ga, Ge, Mo, Of
2 L-1216/2010 Vitreous Endophthalmitis Ci +
3 L-2561/2013 Vitreous Endophthalmitis None +
4 L-1920/2011 Corneal scraping Keratitis Am, Ce, Cef, Ch, Ci, Ga, Ge, Mo, Of +
5 L-3781/2010 Vitreous Endophthalmitis Ce +
6 L-3484/2010 Vitreous Endophthalmitis None
7 L-1573/2013 Vitreous Endophthalmitis Ci, Mo, Of +
8 L-494/2011 Vitreous Endophthalmitis Am, Ce, Cef, Ci, Ga, Ge, Mo, Of +
9 L-223/2014 Corneal scraping Keratitis Ce, Cef, Ci, Ga, Mo, Of +
10 L-304/2014 Corneal scraping Keratitis Ce, Cef +
11 L-811/2014 Lacrimal sac Dacryocystitis Ce, Cef, Ci, Ga, Ge, Mo, Of +
12 L-823/2014 Corneal scraping Keratitis Cef +
  1. The antibiotics used are (µg/disc): Am amikacin (30), Ce ceftazidime (30), Cef cefuroxime (30), Ch chloramphenicol (30), Ci ciprofloxacin (5), Ga gatifloxacin (5), Ge gentamicin (10), Mo moxifloxacin (5) and Of ofloxacin (5)
  2. +, biofilm positive strains (black colonies); −, biofilm negative strains (red or pink colonies). biofilm positive strains (OD > 0.3 at 595 nm); −, biofilm negative strains (OD < 0.3) at 595 nm. The OD of the control wells was deducted in each case