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Table 2 The number of CagL variants in GC and non-GC isolates

From: Genetic variants of Helicobacter pylori type IV secretion system components CagL and CagI and their association with clinical outcomes

Residue Reference Variant GC (n = 10) (%) non-GC (n = 30) (%) p value (GC versus non-GC)
4 Leu Phe 1 10 2 6.7 NS
19 Met Va1 1 10 0 0 NS
28 Lys Arg 0 0 2 6.7 NS
32 Ser Arg 0 0 2 6.7 NS
Asn 2 20 0 0 NS
35 Gln Lys 10 100 29 96.7 NS
41 Val Ala 2 20 0 0 NS
54 Pro Ser 0 0 1 3.3 NS
58 Asn Asp 8 80 30 100 NS
Tyr 1 10 0 0 NS
59 Glu Lys 2 20 25 83.3 0.001
Asn 1 10 1 3.3 NS
60 Met Ile 9 90 30 100 NS
Thr 1 10 0 0 NS
62 Glu Lys 8 80 30 100 NS
Gln 1 10 0 0 NS
65 Ala Ser 0 0 6 20 NS
78 Asp Asn 0 0 1 3.3 NS
88 Ala Thr 3 30 0 0 <0.05
98 Val Met 0 0 2 6.7 NS
101 Lys Asn 3 30 0 0 <0.05
108 Glu Asp 1 10 1 3.3 NS
122 Asn Lys 9 90 28 93.3 NS
Glu 0 0 1 3.3 NS
141 Gly Ala 5 50 0 0 <0.001
142 Lys Glu 5 50 0 0 <0.001
144 Lys Gln 1 10 0 0 NS
154 Glu Asp 0 0 2 6.7 NS
158 Thr Ala 1 10 1 3.3 NS
162 Ala Thr 0 0 1 3.3 NS
167 Ile Val 0 0 1 3.3 NS
171 Ala Thr 0 0 1 3.3 NS
181 Val Ile 2 20 0 0 NS
201 Asn Asp 3 30 24 80 <0.05
203 Val Ile 1 10 3 10 NS
210 Glu Lys 8 80 27 90 NS
216 Arg Ile 10 100 28 93.3 NS
221 Ser Asn 2 20 4 13.3 NS
223 Arg Gln 0 0 1 3.3 NS
234 Ile Val 3 30 23 76.7 <0.05
  1. Statistical analysis was performed by Fisher’s exact test. Residue 234 is a part of the C-terminal motif in the distal six amino acids of CagL
  2. GC gastric cancer, NS not significant