Genetic variants of Helicobacter pylori type IV secretion system components CagL and CagI and their association with clinical outcomes

Table 3 Seven variants of CagL in GC and non-GC isolates without 5 Vietnamese isolates

Residue	Reference	Variant	GC (n = 5)	(%)	non-GC (n = 30)	(%)	p value (GC versus non-GC)
59	Glu	Lys	1	20.0	25	83.3	<0.05
88	Ala	Thr	1	20.0	0	0.0	NS
101	Lys		0	0	0	0	ND
141	Gly		0	0	0	0	ND
142	Lys		0	0	0	0	ND
201	Asn	Asp	3	60.0	24	80.0	NS
234	Ile	Val	2	40.0	23	76.7	NS

Statistical analysis was performed by Fisher’s exact test. Residue 234 is a part of the C-terminal motif in the distal six amino acids of CagL
GC gastric cancer, NS not significant, ND not determined

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