Residue | Reference | Variant | GC (n = 10) | (%) | non-GC (n = 30) | (%) | p value (GC versus non-GC) |
---|---|---|---|---|---|---|---|
1 | Val | Glu | 1 | 10 | 0 | 0 | NS |
2 | Lys | Met | 1 | 10 | 0 | 0 | NS |
3 | Cys | Phe | 1 | 10 | 0 | 0 | NS |
Tyr | 0 | 0 | 1 | 3.3 | NS | ||
5 | Leu | Lys | 1 | 10 | 0 | 0 | NS |
6 | Ser | His | 1 | 10 | 0 | 0 | NS |
7 | Ile | Val | 0 | 0 | 1 | 3.3 | NS |
10 | Phe | Phe | 0 | 0 | 1 | 3.3 | NS |
15 | Gly | Ser | 0 | 0 | 1 | 3.3 | NS |
17 | Ser | Phe | 9 | 90 | 28 | 93.3 | NS |
21 | Thr | Thr | 3 | 30 | 7 | 23.3 | NS |
22 | Glu | Gly | 1 | 10 | 8 | 26.7 | NS |
23 | Val | Ala | 8 | 80 | 26 | 86.7 | NS |
29 | Pro | Ser | 9 | 90 | 28 | 93.3 | NS |
36 | Ala | Val | 0 | 0 | 1 | 3.3 | NS |
40 | Ala | Val | 0 | 0 | 1 | 3.3 | NS |
57 | Ser | Asn | 1 | 10 | 2 | 6.7 | NS |
65 | Ala | Val | 1 | 10 | 1 | 3.3 | NS |
70 | Glu | Gln | 5 | 50 | 25 | 83.3 | NS |
78 | Met | Ile | 9 | 90 | 27 | 90 | NS |
94 | Gly | Ser | 10 | 100 | 30 | 100 | NS |
102 | Gly | Ala | 0 | 0 | 1 | 3.3 | NS |
109 | Val | Ile | 2 | 20 | 12 | 40 | NS |
125 | Lys | Asn | 9 | 90 | 27 | 90 | NS |
152 | Ile | Met | 7 | 70 | 19 | 63.3 | NS |
165 | Glu | Gln | 1 | 10 | 0 | 0 | NS |
179 | Thr | Ala | 1 | 10 | 0 | 0 | NS |
182 | Glu | Ala | 0 | 0 | 1 | 3.3 | NS |
190 | Ser | Asn | 0 | 0 | 1 | 3.3 | NS |
195 | Ala | Thr | 0 | 0 | 4 | 13.3 | NS |
196 | Gln | Lys | 8 | 80 | 26 | 86.7 | NS |
203 | Ile | Val | 1 | 10 | 0 | 0 | NS |
207 | Ala | Thr | 0 | 0 | 1 | 3.3 | NS |
213 | Lys | Glu | 1 | 10 | 1 | 3.3 | NS |
214 | Gly | Asp | 0 | 0 | 1 | 3.3 | NS |
221 | Val | Ala | 3 | 30 | 3 | 10 | NS |
222 | Ala | Thr | 0 | 0 | 1 | 3.3 | NS |
238 | Ala | Asp | 3 | 30 | 9 | 30 | NS |
Thr | 0 | 0 | 1 | 3.3 | NS | ||
243 | Ala | Thr | 0 | 0 | 1 | 3.3 | NS |
Val | 0 | 0 | 1 | 3.3 | NS | ||
246 | Ala | Glu | 5 | 50 | 19 | 63.3 | NS |
Val | 0 | 0 | 1 | 3.3 | NS | ||
262 | Ile | Val | 2 | 20 | 14 | 46.7 | NS |
294 | Met | Lys | 9 | 90 | 30 | 100 | NS |
304 | Ser | Asn | 9 | 90 | 30 | 100 | NS |
319 | Gly | Glu | 9 | 90 | 30 | 100 | NS |
346 | Asn | Ser | 0 | 0 | 1 | 3.3 | NS |
368 | Thr | Ala | 0 | 0 | 1 | 3.3 | NS |
Met | 1 | 10 | 0 | 0 | NS |