Fig. 2From: Helicobacter pylori vacA s1m1 genotype but not cagA or babA2 increase the risk of ulcer and gastric cancer in patients from Southern MexicoForward primer binding to babA2 and babA1 gene sequences. Detection of bab2A gene is determined by perfect match of 3′- end from forward primer. Differences between babA2 and bab1 sequences are shown in the increased font size and matches are indicated by vertical bars; mismatches are indicated by asterisks. babA1 and babA2 have almost complete sequence homology, with the exception of an approximately 10 bp insert, found only in babA2, which creates a translational initiation codon in the signal peptide sequence. Gerhard et al. used this sequence difference to amplify the babA2 gene selectively by mismatch PCR [16]Back to article page