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Table 4 The associations between virulence genes and resistance phenotypes among Escherichia coli in phylogenetic group A (n = 232)

From: Antibiotic resistance, serogroups, virulence genes, and phylogenetic groups of Escherichia coli isolated from yaks with diarrhea in Qinghai Plateau, China

Virulence gene (n)

Associations of gene (OR, 95% confidence interval)*,a

No.

AMP

No.

TET

No.

GEN

No.

CHP

No.

CEF

No.

SXT

No.

STR

No.

CIP

sfa (223)

214

–

195

–

186

–

180

–

157

–

129

0.07 (0.0–1.2)

123

0.06 (0.0–0.1)

90

0.03 (0.0–0.6)

eaeA (174)

165

–

161

4.3 (1.9–9.8)

144

–

137

–

135

3.01 (1.6–5.6)

120

4.9 (2.6–9.4)

101

–

86

3.4 (1.7–6.7)

cnf1 (122)

122

22.9 (1.3–398.8)

113

2.6 (1.1–6.1)

110

2.7 (1.3–5.7)

79

0.008 (0.0–0.1)

91

–

76

–

84

2.8 (1.7–4.9)

53

–

etrA (69)

60

0.02 (0.0–0.3)

65

–

55

–

43

0.2 (0.1–0.4)

56

2.1 (1.04–4.1)

31

0.4 (0.2–0.7)

39

–

39

2.2(1.2–3.9)

papC (61)

52

0.02 (0.0–0.3)

52

–

42

0.3 (0.1–0.5)

44

0.3 (0.1-0.6)

40

–

37

–

42

2.0 (1.1–3.7)

16

0.4 (0.2–0.7)

hlyA (39)

30

0.008 (0.0–0.1)

29

0.3 (0.1–0.7)

27

0.3 (0.1–0.7)

21

0.2 (0.08–0.4)

27

–

12

0.2 (0.1-0.5)

22

–

18

–

aer (36)

36

–

26

0.3 (0.1–0.6)

24

0.3 (0.1–0.6)

14

0.08 (0.03–0.2)

22

–

33

9.5 (2.8-32.1)

26

2.2 (1.01–4.8)

11

–

faeG (9)

09

–

07

–

02

0.04 (0.0–0.2)

06

–

06

–

08

–

07

–

02

–

rfc/sepA (2)

02

–

02

–

02

–

02

–

02

–

02

–

02

–

02

–

  1. –, indicates no significant associations (P ≥ 0.05); AMP, ampicillin; TET, tetracycline; GEN, gentamicin; CHP, chloramphenicol; CEF, ceftriaxone; SXT, trimethoprim/sulfamethoxazole; STR, streptomycin; CIP, ciprofloxacin
  2. * Only antibiotic-resistant phenotypes with a significant association (P < 0.05) with the virulence genes in phylogenetic group A are shown
  3. aOdds ratio (OR) for significant associations between genes (95% confidence interval in parenthesis)