Table 6 Number of animals with histopathological alterations
|  | Negative; n = 3 | E. coli O104:H4; n = 6 | E. coli O157:H7; n = 4 |
|---|---|---|---|
CNS | |||
 Neuropil vacuolization | 3 | 5 | 4 |
 Submeningeal oedema | 0 | 0 | 1 |
 Perivascular oedema | 1 | 5 | 2 |
 Focal liquefaction necrosis in the brainstem | 0 | 0 | 1 |
 Acute white matter spongiosis in cerebellum/brainstem | 0 | 0 | 1 |
Kidney | |||
 Thrombosis of renal arterioles | 0 | 3 | 2 |
Colon ascendens | |||
 Submucosal oedema | 3 | 4 | 3 |
 Subserosal oedema | 1 | 4 | 2 |
 Crypt hypoplasia | 0 | 2 | 0 |
 Haematoidin/siderin/siderophages | 0 | 2 | 0 |
 Lymphoplasmocytic infiltration of the propria | 0 | 2 | 1 |