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Fig. 4 | Gut Pathogens

Fig. 4

From: Immune responses upon Campylobacter jejuni infection of secondary abiotic mice lacking nucleotide-oligomerization-domain-2

Fig. 4

Colonic secretion of pro- and anti-inflammatory cytokines in C. jejuni infected secondary abiotic Nod2−/− mice. Secondary abiotic wildtype (WT; white circles) and Nod2−/− mice (black circles) were generated by broad-spectrum antibiotic treatment and perorally infected with C. jejuni strain 81-176 by gavage at day (d) 0 and d1. a Nitric oxide, b TNF, c IFN-γ, d MCP-1, e IL-6 and f IL-10 concentrations were determined in supernatants of colonic ex vivo biopsies at day 7 postinfection. Naive (N) secondary abiotic mice served as uninfected controls. Medians (black bars), level of significance (p-value) determined by Mann–Whitney U test and numbers of analyzed animals (in parentheses) are indicated. Data were pooled from four independent experiments

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Gut Pathogens

ISSN: 1757-4749