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Fig. 1 | Gut Pathogens

Fig. 1

From: Anaerobic adaptation of Mycobacterium avium subspecies paratuberculosis in vitro: similarities to M. tuberculosis and differential susceptibility to antibiotics

Fig. 1

Growth and adaptation of MAP versus M. bovis BCG in the in vitro Wayne model of anaerobiosis. CFU/ml colony forming units per ml of culture, OD optical density of broth culture when read at A600 nm. Lines indicate CFUs/ml, bars indicate OD A600. Data shown for MAP strains ATCC 19698 and 43544 as well as B-1, B-2, B-3, and BCG (M. bovis BCG ATCC 35734). Fading of methylene blue occurred for all strains tested between 12 and 14 days; complete decolorization occurred for all strains between days 18 and 19 indicating anerobiosis. All strains tested exhibited a continued increase in OD A600 at the same point in time at which CFUs were leveling off consistent with adaptation to anaerobiosis and non-replicating persistence

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