TY - JOUR AU - Robinson, K. AU - Letley, D. P. AU - Kaneko, K. PY - 2017 DA - 2017// TI - The human stomach in health and disease: infection strategies by Helicobacter pylori JO - Curr Top Microbiol Immunol VL - 400 ID - Robinson2017 ER - TY - JOUR AU - Mejías-Luque, R. AU - Gerhard, M. PY - 2017 DA - 2017// TI - Immune evasion strategies and persistence of Helicobacter pylori JO - Curr Top Microbiol Immunol VL - 400 ID - Mejías-Luque2017 ER - TY - JOUR AU - Salama, N. R. AU - Hartung, M. L. AU - Müller, A. PY - 2013 DA - 2013// TI - Life in the human stomach: persistence strategies of the bacterial pathogen Helicobacter pylori JO - Nat Rev Microbiol VL - 11 UR - https://doi.org/10.1038/nrmicro3016 DO - 10.1038/nrmicro3016 ID - Salama2013 ER - TY - JOUR AU - Figueiredo, C. AU - Camargo, C. M. AU - Leite, M. AU - Fuentes-Pananá, E. M. AU - Rabkin, C. S. AU - Machado, J. C. PY - 2017 DA - 2017// TI - Pathogenesis of gastric cancer: genetics and molecular classification JO - Curr Top Microbiol Immunol VL - 400 ID - Figueiredo2017 ER - TY - JOUR AU - Cover, T. L. AU - Peek, R. M. PY - 2013 DA - 2013// TI - Diet, microbial virulence, and Helicobacter pylori-induced gastric cancer JO - Gut Microbes VL - 4 UR - https://doi.org/10.4161/gmic.26262 DO - 10.4161/gmic.26262 ID - Cover2013 ER - TY - JOUR AU - Backert, S. AU - Blaser, M. J. PY - 2016 DA - 2016// TI - The role of CagA in the gastric biology of Helicobacter pylori JO - Cancer Res VL - 76 UR - https://doi.org/10.1158/0008-5472.CAN-16-1680 DO - 10.1158/0008-5472.CAN-16-1680 ID - Backert2016 ER - TY - JOUR AU - Gobert, A. P. AU - Wilson, K. T. PY - 2017 DA - 2017// TI - Human and Helicobacter pylori interactions determine the outcome of gastric diseases JO - Curr Top Microbiol Immunol VL - 400 ID - Gobert2017 ER - TY - JOUR AU - Backert, S. AU - Tegtmeyer, N. AU - Fischer, W. PY - 2015 DA - 2015// TI - Composition, structure and function of the Helicobacter pylori cag pathogenicity island encoded type IV secretion system JO - Future Microbiol VL - 10 UR - https://doi.org/10.2217/fmb.15.32 DO - 10.2217/fmb.15.32 ID - Backert2015 ER - TY - JOUR AU - Bergé, C. AU - Terradot, L. PY - 2017 DA - 2017// TI - Structural insights into Helicobacter pylori Cag protein interactions with host cell factors JO - Curr Top Microbiol Immunol VL - 400 ID - Bergé2017 ER - TY - JOUR AU - Backert, S. AU - Feller, S. M. AU - Wessler, S. PY - 2008 DA - 2008// TI - Emerging roles of Abl family tyrosine kinases in microbial pathogenesis JO - Trends Biochem Sci VL - 33 UR - https://doi.org/10.1016/j.tibs.2007.10.006 DO - 10.1016/j.tibs.2007.10.006 ID - Backert2008 ER - TY - JOUR AU - Lind, J. AU - Backert, S. AU - Pfleiderer, K. AU - Berg, D. E. AU - Yamaoka, Y. AU - Sticht, H. PY - 2014 DA - 2014// TI - Systematic analysis of phosphotyrosine antibodies recognizing single phosphorylated EPIYA-motifs in CagA of Western-type Helicobacter pylori strains JO - PLoS ONE VL - 9 UR - https://doi.org/10.1371/journal.pone.0096488 DO - 10.1371/journal.pone.0096488 ID - Lind2014 ER - TY - JOUR AU - Lind, J. AU - Backert, S. AU - Hoffmann, R. AU - Eichler, J. AU - Yamaoka, Y. AU - Perez-Perez, G. I. PY - 2016 DA - 2016// TI - Systematic analysis of phosphotyrosine antibodies recognizing single phosphorylated EPIYA-motifs in CagA of East Asian-type Helicobacter pylori strains JO - BMC Microbiol VL - 16 UR - https://doi.org/10.1186/s12866-016-0820-6 DO - 10.1186/s12866-016-0820-6 ID - Lind2016 ER - TY - JOUR AU - Mueller, D. AU - Tegtmeyer, N. AU - Brandt, S. AU - Yamaoka, Y. AU - Poire, E. AU - Sgouras, D. PY - 2012 DA - 2012// TI - c-Src and c-Abl kinases control hierarchic phosphorylation and function of the CagA effector protein in western and East Asian Helicobacter pylori strains JO - J Clin Invest VL - 122 UR - https://doi.org/10.1172/JCI61143 DO - 10.1172/JCI61143 ID - Mueller2012 ER - TY - JOUR AU - Hatakeyama, M. PY - 2014 DA - 2014// TI - Helicobacter pylori CagA and gastric cancer: a paradigm for hit-and-run carcinogenesis JO - Cell Host Microbe VL - 15 UR - https://doi.org/10.1016/j.chom.2014.02.008 DO - 10.1016/j.chom.2014.02.008 ID - Hatakeyama2014 ER - TY - JOUR AU - Viala, J. AU - Chaput, C. AU - Boneca, I. G. AU - Cardona, A. AU - Girardin, S. E. AU - Moran, A. P. PY - 2004 DA - 2004// TI - Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island JO - Nat Immunol VL - 5 UR - https://doi.org/10.1038/ni1131 DO - 10.1038/ni1131 ID - Viala2004 ER - TY - JOUR AU - Brandt, S. AU - Kwok, T. AU - Hartig, R. AU - König, W. AU - Backert, S. PY - 2005 DA - 2005// TI - NF-kappaB activation and potentiation of proinflammatory responses by the Helicobacter pylori CagA protein JO - Proc Natl Acad Sci USA VL - 102 UR - https://doi.org/10.1073/pnas.0409873102 DO - 10.1073/pnas.0409873102 ID - Brandt2005 ER - TY - JOUR AU - Backert, S. AU - Naumann, M. PY - 2010 DA - 2010// TI - What a disorder: proinflammatory signaling pathways induced by Helicobacter pylori JO - Trends Microbiol VL - 18 UR - https://doi.org/10.1016/j.tim.2010.08.003 DO - 10.1016/j.tim.2010.08.003 ID - Backert2010 ER - TY - JOUR AU - Posselt, G. AU - Backert, S. AU - Wessler, S. PY - 2013 DA - 2013// TI - The functional interplay of Helicobacter pylori factors with gastric epithelial cells induces a multi-step process in pathogenesis JO - Cell Commun Signal VL - 11 UR - https://doi.org/10.1186/1478-811X-11-77 DO - 10.1186/1478-811X-11-77 ID - Posselt2013 ER - TY - JOUR AU - Rad, R. AU - Gerhard, M. AU - Lang, R. AU - Schöniger, M. AU - Rösch, T. AU - Schepp, W. PY - 2002 DA - 2002// TI - The Helicobacter pylori blood group antigen-binding adhesin facilitates bacterial colonization and augments a nonspecific immune response JO - J Immunol VL - 168 UR - https://doi.org/10.4049/jimmunol.168.6.3033 DO - 10.4049/jimmunol.168.6.3033 ID - Rad2002 ER - TY - JOUR AU - Backert, S. AU - Clyne, M. AU - Tegtmeyer, N. PY - 2011 DA - 2011// TI - Molecular mechanisms of gastric epithelial cell adhesion and injection of CagA by Helicobacter pylori JO - Cell Commun Signal VL - 9 UR - https://doi.org/10.1186/1478-811X-9-28 DO - 10.1186/1478-811X-9-28 ID - Backert2011 ER - TY - JOUR AU - Ricci, V. AU - Giannouli, M. AU - Romano, M. AU - Zarrilli, R. PY - 2014 DA - 2014// TI - Helicobacter pylori gamma-glutamyl transpeptidase and its pathogenic role JO - World J Gastroenterol VL - 20 UR - https://doi.org/10.3748/wjg.v20.i3.630 DO - 10.3748/wjg.v20.i3.630 ID - Ricci2014 ER - TY - JOUR AU - Frees, D. AU - Brøndsted, L. AU - Ingmer, H. PY - 2013 DA - 2013// TI - Bacterial proteases and virulence JO - Subcell Biochem VL - 66 UR - https://doi.org/10.1007/978-94-007-5940-4_7 DO - 10.1007/978-94-007-5940-4_7 ID - Frees2013 ER - TY - STD TI - Skórko-Glonek J, Figaj D, Zarzecka U, Przepiora T, Renke J, Lipinska B. The extracellular bacterial HtrA proteins as potential therapeutic targets and vaccine candidates. Curr Med Chem. 2016 (Epub ahead of print). ID - ref23 ER - TY - JOUR AU - Wessler, S. AU - Schneider, G. AU - Backert, S. PY - 2017 DA - 2017// TI - Bacterial serine protease HtrA as a promising new target for antimicrobial therapy? JO - Cell Commun Signal VL - 15 UR - https://doi.org/10.1186/s12964-017-0162-5 DO - 10.1186/s12964-017-0162-5 ID - Wessler2017 ER - TY - JOUR AU - Gottesman, S. AU - Wickner, S. AU - Maurizi, M. R. PY - 1997 DA - 1997// TI - Protein quality control: triage by chaperone and proteases JO - Genes Dev VL - 11 UR - https://doi.org/10.1101/gad.11.7.815 DO - 10.1101/gad.11.7.815 ID - Gottesman1997 ER - TY - JOUR AU - Ingmer, H. AU - Brøndsted, L. PY - 2009 DA - 2009// TI - Proteases in bacterial pathogenesis JO - Res Microbiol VL - 160 UR - https://doi.org/10.1016/j.resmic.2009.08.017 DO - 10.1016/j.resmic.2009.08.017 ID - Ingmer2009 ER - TY - JOUR AU - Clausen, T. AU - Southan, C. AU - Ehrmann, M. PY - 2002 DA - 2002// TI - The HtrA family of proteases: implications for protein composition and cell fate JO - Mol Cell VL - 10 UR - https://doi.org/10.1016/S1097-2765(02)00658-5 DO - 10.1016/S1097-2765(02)00658-5 ID - Clausen2002 ER - TY - JOUR AU - Kim, D. Y. AU - Kim, K. K. PY - 2005 DA - 2005// TI - Structure and function of HtrA family proteins, the key players in protein quality control JO - J Biochem Mol Biol VL - 38 ID - Kim2005 ER - TY - JOUR AU - Backert, S. AU - Boehm, M. AU - Wessler, S. AU - Tegtmeyer, N. PY - 2013 DA - 2013// TI - Transmigration route of Campylobacter jejuni across polarized intestinal epithelial cells: paracellular, transcellular or both? JO - Cell Commun Signal VL - 11 UR - https://doi.org/10.1186/1478-811X-11-72 DO - 10.1186/1478-811X-11-72 ID - Backert2013 ER - TY - JOUR AU - Lipinska, B. AU - Fayet, O. AU - Baird, L. AU - Georgopoulos, C. J. PY - 1989 DA - 1989// TI - Identification, characterization, and mapping of the Escherichia coli htrA gene, whose product is essential for bacterial growth only at elevated temperatures JO - Bacteriol VL - 171 UR - https://doi.org/10.1128/jb.171.3.1574-1584.1989 DO - 10.1128/jb.171.3.1574-1584.1989 ID - Lipinska1989 ER - TY - JOUR AU - Pedersen, L. L. AU - Radulic, M. AU - Doric, M. AU - Kwaik, Y. A. PY - 2001 DA - 2001// TI - HtrA homologue of Legionella pneumophila: an indispensable element for intracellular infection of mammalian but not protozoan cells JO - Infect Immun VL - 69 UR - https://doi.org/10.1128/IAI.69.4.2569-2579.2001 DO - 10.1128/IAI.69.4.2569-2579.2001 ID - Pedersen2001 ER - TY - JOUR AU - Cortés, G. AU - Astorza, B. AU - Benedí, V. J. AU - Albertí, S. PY - 2002 DA - 2002// TI - Role of the htrA gene in Klebsiella pneumoniae virulence JO - Infect Immun VL - 70 UR - https://doi.org/10.1128/IAI.70.9.4772-4776.2002 DO - 10.1128/IAI.70.9.4772-4776.2002 ID - Cortés2002 ER - TY - JOUR AU - Mo, E. AU - Peters, S. E. AU - Willers, C. AU - Maskell, D. J. AU - Charles, I. G. PY - 2007 DA - 2007// TI - Single, double and triple mutants of Salmonella enterica serovar Typhimurium degP (htrA), degQ (hhoA) and degS (hhoB) have diverse phenotypes on exposure to elevated temperature and their growth in vivo is attenuated to different extents JO - Infect Immun VL - 75 UR - https://doi.org/10.1128/IAI.01581-06 DO - 10.1128/IAI.01581-06 ID - Mo2007 ER - TY - JOUR AU - Flannagan, R. S. AU - Aubert, D. AU - Kooi, C. AU - Sokol, P. A. AU - Valvano, M. A. PY - 2007 DA - 2007// TI - Burkholderia cenocepacia requires a periplasmic HtrA protease for growth under thermal and osmotic stress and for survival in vivo JO - Infect Immun VL - 75 UR - https://doi.org/10.1128/IAI.01581-06 DO - 10.1128/IAI.01581-06 ID - Flannagan2007 ER - TY - JOUR AU - Boehm, M. AU - Lind, J. AU - Backert, S. AU - Tegtmeyer, N. PY - 2015 DA - 2015// TI - Campylobacter jejuni serine protease HtrA plays an important role in heat tolerance, oxygen resistance, host cell adhesion, invasion, and transmigration JO - Eur J Microbiol Immunol (Bp) VL - 5 UR - https://doi.org/10.1556/EuJMI-D-15-00003 DO - 10.1556/EuJMI-D-15-00003 ID - Boehm2015 ER - TY - JOUR AU - Löwer, M. AU - Weydig, C. AU - Metzler, D. AU - Reuter, A. AU - Starzinski-Powitz, A. AU - Wessler, S. PY - 2008 DA - 2008// TI - Prediction of extracellular proteases of the human pathogen Helicobacter pylori reveals proteolytic activity of the Hp1018/19 protein HtrA JO - PLoS ONE VL - 3 UR - https://doi.org/10.1371/journal.pone.0003510 DO - 10.1371/journal.pone.0003510 ID - Löwer2008 ER - TY - JOUR AU - Hoy, B. AU - Löwer, M. AU - Weydig, C. AU - Carra, G. AU - Tegtmeyer, N. AU - Geppert, T. PY - 2010 DA - 2010// TI - Helicobacter pylori HtrA is a new secreted virulence factor that cleaves E-cadherin to disrupt intercellular adhesion JO - EMBO Rep VL - 11 UR - https://doi.org/10.1038/embor.2010.114 DO - 10.1038/embor.2010.114 ID - Hoy2010 ER - TY - JOUR AU - Hoy, B. AU - Geppert, T. AU - Boehm, M. AU - Reisen, F. AU - Plattner, P. AU - Gadermaier, G. PY - 2012 DA - 2012// TI - Distinct roles of secreted HtrA proteases from gram-negative pathogens in cleaving the junctional protein and tumor suppressor E-cadherin JO - J Biol Chem VL - 23 UR - https://doi.org/10.1074/jbc.C111.333419 DO - 10.1074/jbc.C111.333419 ID - Hoy2012 ER - TY - JOUR AU - Boehm, M. AU - Hoy, B. AU - Rohde, M. AU - Tegtmeyer, N. AU - Bæk, K. T. AU - Oyarzabal, O. A. PY - 2012 DA - 2012// TI - Rapid paracellular transmigration of Campylobacter jejuni across polarized epithelial cells without affecting TER: role of proteolytic-active HtrA cleaving E-cadherin but not fibronectin JO - Gut Pathog VL - 4 UR - https://doi.org/10.1186/1757-4749-4-3 DO - 10.1186/1757-4749-4-3 ID - Boehm2012 ER - TY - JOUR AU - Schmidt, T. P. AU - Perna, A. M. AU - Fugmann, T. AU - Boehm, M. AU - Hiss, J. a. n. AU - Haller, S. PY - 2016 DA - 2016// TI - Identification of E-cadherin signature motifs functioning as cleavage sites for Helicobacter pylori HtrA JO - Sci Rep VL - 6 UR - https://doi.org/10.1038/srep23264 DO - 10.1038/srep23264 ID - Schmidt2016 ER - TY - JOUR AU - Abfalter, C. M. AU - Schubert, M. AU - Götz, C. AU - Schmidt, T. P. AU - Posselt, G. AU - Wessler, S. PY - 2016 DA - 2016// TI - HtrA-mediated E-cadherin cleavage is limited to DegP and DegQ homologs expressed by gram-negative pathogens JO - Cell Commun Signal VL - 14 UR - https://doi.org/10.1186/s12964-016-0153-y DO - 10.1186/s12964-016-0153-y ID - Abfalter2016 ER - TY - JOUR AU - Backert, S. AU - Schmidt, T. P. AU - Harrer, A. AU - Wessler, S. PY - 2017 DA - 2017// TI - Exploiting the gastric epithelial barrier: Helicobacter pylori’s attack on tight and adherens junctions JO - Curr Top Microbiol Immunol VL - 400 ID - Backert2017 ER - TY - JOUR AU - Heimesaat, M. M. AU - Alutis, M. AU - Grundmann, U. AU - Fischer, A. AU - Tegtmeyer, N. AU - Boehm, M. PY - 2014 DA - 2014// TI - The role of serine protease HtrA in acute ulcerative enterocolitis and extra-intestinal immune responses during Campylobacter jejuni infection of gnotobiotic IL-10 deficient mice JO - Front Cell Infect Microbiol VL - 4 UR - https://doi.org/10.3389/fcimb.2014.00077 DO - 10.3389/fcimb.2014.00077 ID - Heimesaat2014 ER - TY - JOUR AU - Heimesaat, M. M. AU - Fischer, A. AU - Alutis, M. AU - Grundmann, U. AU - Boehm, M. AU - Tegtmeyer, N. PY - 2014 DA - 2014// TI - The impact of serine protease HtrA in apoptosis, intestinal immune responses and extra-intestinal histopathology during Campylobacter jejuni infection of infant mice JO - Gut Pathog VL - 6 UR - https://doi.org/10.1186/1757-4749-6-16 DO - 10.1186/1757-4749-6-16 ID - Heimesaat2014 ER - TY - JOUR AU - Li, S. R. AU - Dorrell, N. AU - Everest, P. H. AU - Dougan, G. AU - Wren, B. W. PY - 1996 DA - 1996// TI - Construction and characterization of a Yersinia enterocolitica O:8 high-temperature requirement (htrA) isogenic mutant JO - Infect Immun VL - 64 ID - Li1996 ER - TY - JOUR AU - Humphreys, S. AU - Stevenson, A. AU - Bacon, A. AU - Weinhardt, A. B. AU - Roberts, M. PY - 1999 DA - 1999// TI - The alternative sigma factor, sigmaE, is critically important for the virulence of Salmonella typhimurium JO - Infect Immun VL - 67 ID - Humphreys1999 ER - TY - JOUR AU - Purdy, G. E. AU - Hong, M. AU - Payne, S. M. PY - 2002 DA - 2002// TI - Shigella flexneri DegP facilitates IcsA surface expression and is required for efficient intercellular spread JO - Infect Immun VL - 70 UR - https://doi.org/10.1128/IAI.70.11.6355-6364.2002 DO - 10.1128/IAI.70.11.6355-6364.2002 ID - Purdy2002 ER - TY - JOUR AU - Wilson, R. L. AU - Brown, L. L. AU - Kirkwood-watts, D. AU - Warren, T. K. AU - Lund, S. A. AU - King, D. S. PY - 2006 DA - 2006// TI - Listeria monocytogenes 10403S HtrA is necessary for resistance to cellular stress and virulence JO - Microbiology VL - 74 ID - Wilson2006 ER - TY - JOUR AU - Gloeckl, S. AU - Ong, V. A. AU - Patel, P. AU - Tyndall, J. D. AU - Timms, P. AU - Beagley, K. W. PY - 2013 DA - 2013// TI - Identification of a serine protease inhibitor which causes inclusion vacuole reduction and is lethal to Chlamydia trachomatis JO - Mol Microbiol VL - 89 UR - https://doi.org/10.1111/mmi.12306 DO - 10.1111/mmi.12306 ID - Gloeckl2013 ER - TY - JOUR AU - Ye, M. AU - Sharma, K. AU - Thakur, M. AU - Smith, A. A. AU - Buyuktanir, O. AU - Xiang, X. PY - 2016 DA - 2016// TI - HtrA, a temperature- and stationary phase-activated protease involved in maturation of a key microbial virulence determinant, facilitates Borrelia burgdorferi infection in mammalian hosts JO - Infect Immun VL - 84 UR - https://doi.org/10.1128/IAI.00360-16 DO - 10.1128/IAI.00360-16 ID - Ye2016 ER - TY - JOUR AU - Salama, N. R. AU - Shepherd, B. AU - Falkow, S. PY - 2004 DA - 2004// TI - Global transposon mutagenesis and essential gene analysis of Helicobacter pylori JO - J Bacteriol VL - 186 UR - https://doi.org/10.1128/JB.186.23.7926-7935.2004 DO - 10.1128/JB.186.23.7926-7935.2004 ID - Salama2004 ER - TY - JOUR AU - Tegtmeyer, N. AU - Moodley, Y. AU - Yamaoka, Y. AU - Pernitzsch, S. R. AU - Schmidt, V. AU - Traverso, F. R. PY - 2016 DA - 2016// TI - Characterisation of worldwide Helicobacter pylori strains reveals genetic conservation and essentiality of serine protease HtrA JO - Mol Microbiol VL - 99 UR - https://doi.org/10.1111/mmi.13276 DO - 10.1111/mmi.13276 ID - Tegtmeyer2016 ER - TY - JOUR AU - Boneca, I. G. AU - Ecobichon, C. AU - Chaput, C. AU - Mathieu, A. AU - Guadagnini, S. AU - Prévost, M. C. PY - 2008 DA - 2008// TI - Development of inducible systems to engineer conditional mutants of essential genes of Helicobacter pylori JO - Appl Environ Microbiol VL - 74 UR - https://doi.org/10.1128/AEM.01348-07 DO - 10.1128/AEM.01348-07 ID - Boneca2008 ER - TY - JOUR AU - Backert, S. AU - Ziska, E. AU - Brinkmann, V. AU - Zimny-Arndt, U. AU - Fauconnier, A. AU - Jungblut, P. R. PY - 2000 DA - 2000// TI - Translocation of the Helicobacter pylori CagA protein in gastric epithelial cells by a type IV secretion apparatus JO - Cell Microbiol VL - 2 UR - https://doi.org/10.1046/j.1462-5822.2000.00043.x DO - 10.1046/j.1462-5822.2000.00043.x ID - Backert2000 ER - TY - JOUR AU - Kwok, T. AU - Backert, S. AU - Schwarz, H. AU - Berger, J. AU - Meyer, T. F. PY - 2002 DA - 2002// TI - Specific entry of Helicobacter pylori into cultured gastric epithelial cells via a zipper-like mechanism JO - Infect Immun VL - 70 UR - https://doi.org/10.1128/IAI.70.4.2108-2120.2002 DO - 10.1128/IAI.70.4.2108-2120.2002 ID - Kwok2002 ER - TY - JOUR AU - Kwok, T. AU - Zabler, D. AU - Urman, S. AU - Rohde, M. AU - Hartig, R. AU - Wessler, S. PY - 2007 DA - 2007// TI - Helicobacter exploits integrin for type IV secretion and kinase activation JO - Nature VL - 449 UR - https://doi.org/10.1038/nature06187 DO - 10.1038/nature06187 ID - Kwok2007 ER - TY - JOUR AU - Jiménez-Soto, L. F. AU - Kutter, S. AU - Sewald, X. AU - Ertl, C. AU - Weiss, E. AU - Kapp, U. PY - 2009 DA - 2009// TI - Helicobacter pylori type IV secretion apparatus exploits beta1 integrin in a novel RGD-independent manner JO - PLoS Pathog VL - 5 UR - https://doi.org/10.1371/journal.ppat.1000684 DO - 10.1371/journal.ppat.1000684 ID - Jiménez-Soto2009 ER - TY - JOUR AU - Saha, A. AU - Backert, S. AU - Hammond, C. E. AU - Gooz, M. AU - Smolka, A. J. PY - 2010 DA - 2010// TI - Helicobacter pylori CagL activates ADAM17 to induce repression of the gastric H, K-ATPase alpha subunit JO - Gastroenterology VL - 139 UR - https://doi.org/10.1053/j.gastro.2010.03.036 DO - 10.1053/j.gastro.2010.03.036 ID - Saha2010 ER - TY - JOUR AU - Conradi, J. AU - Huber, S. AU - Gaus, K. AU - Mertink, F. AU - Royo Gracia, S. AU - Strijowski, U. PY - 2012 DA - 2012// TI - Cyclic RGD peptides interfere with binding of the Helicobacter pylori protein CagL to integrins αVβ3 and α5β1 JO - Amino Acids VL - 43 UR - https://doi.org/10.1007/s00726-011-1066-0 DO - 10.1007/s00726-011-1066-0 ID - Conradi2012 ER - TY - JOUR AU - Conradi, J. AU - Tegtmeyer, N. AU - Woźna, M. AU - Wissbrock, M. AU - Michalek, C. AU - Gagell, C. PY - 2012 DA - 2012// TI - An RGD helper sequence in CagL of Helicobacter pylori assists in interactions with integrins and injection of CagA JO - Front Cell Infect Microbiol VL - 2 UR - https://doi.org/10.3389/fcimb.2012.00070 DO - 10.3389/fcimb.2012.00070 ID - Conradi2012 ER - TY - JOUR AU - Barden, S. AU - Lange, S. AU - Tegtmeyer, N. AU - Conradi, J. AU - Sewald, N. AU - Backert, S. PY - 2013 DA - 2013// TI - A helical RGD motif promoting cell adhesion: crystal structures of the Helicobacter pylori type IV secretion system pilus protein CagL JO - Structure VL - 21 UR - https://doi.org/10.1016/j.str.2013.08.018 DO - 10.1016/j.str.2013.08.018 ID - Barden2013 ER - TY - JOUR AU - Tegtmeyer, N. AU - Lind, J. AU - Schmid, B. AU - Backert, S. PY - 2014 DA - 2014// TI - Helicobacter pylori CagL Y58/E59 mutation turns-off type IV secretion-dependent delivery of CagA into host cells JO - PLoS ONE VL - 9 UR - https://doi.org/10.1371/journal.pone.0097782 DO - 10.1371/journal.pone.0097782 ID - Tegtmeyer2014 ER - TY - JOUR AU - Guo, W. AU - Giancotti, F. G. PY - 2004 DA - 2004// TI - Integrin signalling during tumour progression JO - Nat Rev Mol Cell Biol VL - 5 UR - https://doi.org/10.1038/nrm1490 DO - 10.1038/nrm1490 ID - Guo2004 ER - TY - JOUR AU - Horton, E. R. AU - Humphries, J. D. AU - James, J. AU - Jones, M. C. AU - Askari, J. A. AU - Humphries, M. J. PY - 2016 DA - 2016// TI - The integrin adhesome network at a glance JO - J Cell Sci VL - 129 UR - https://doi.org/10.1242/jcs.192054 DO - 10.1242/jcs.192054 ID - Horton2016 ER - TY - JOUR AU - Li, B. AU - Huang, C. PY - 2017 DA - 2017// TI - Regulation of EMT by STAT3 in gastrointestinal cancer JO - Int J Oncol VL - 50 ID - Li2017 ER - TY - JOUR AU - Saadat, I. AU - Higashi, H. AU - Obuse, C. AU - Murata-Kamiya, N. AU - Umeda, M. AU - Saito, Y. PY - 2007 DA - 2007// TI - Helicobacter pylori CagA targets PAR1/MARK kinase to disrupt epithelial cell polarity JO - Nature VL - 447 UR - https://doi.org/10.1038/nature05765 DO - 10.1038/nature05765 ID - Saadat2007 ER - TY - JOUR AU - Lee, D. G. AU - Kim, H. S. AU - Lee, Y. S. AU - Cha, S. Y. AU - Kim, S. AU - Ota, I. PY - 2014 DA - 2014// TI - H. pylori CagA promotes snail-mediated epithelial-mesenchymal transition by reducing GSK-3 activity JO - Nat Commun VL - 5 ID - Lee2014 ER - TY - JOUR AU - Zhang, Y. M. AU - Noto, J. M. AU - Hammond, C. E. AU - Barth, J. L. AU - Argraves, W. S. AU - Backert, S. PY - 2014 DA - 2014// TI - Helicobacter pylori-induced posttranscriptional regulation of H-K-ATPase α-subunit gene expression by miRNA JO - Am J Physiol Gastrointest Liver Physiol VL - 306 UR - https://doi.org/10.1152/ajpgi.00333.2013 DO - 10.1152/ajpgi.00333.2013 ID - Zhang2014 ER - TY - JOUR AU - Wiedemann, T. AU - Hofbaur, S. AU - Tegtmeyer, N. AU - Huber, S. AU - Sewald, N. AU - Wessler, S. PY - 2012 DA - 2012// TI - Helicobacter pylori CagL dependent induction of gastrin expression via a novel αvβ5-integrin-integrin linked kinase signaling complex JO - Gut VL - 61 UR - https://doi.org/10.1136/gutjnl-2011-300525 DO - 10.1136/gutjnl-2011-300525 ID - Wiedemann2012 ER - TY - JOUR AU - Kim, D. J. AU - Park, J. H. AU - Franchi, L. AU - Backert, S. AU - Núñez, G. PY - 2013 DA - 2013// TI - The Cag pathogenicity island and interaction between TLR2/NOD2 and NLRP3 regulate IL-1β production in Helicobacter pylori infected dendritic cells JO - Eur J Immunol VL - 43 UR - https://doi.org/10.1002/eji.201243281 DO - 10.1002/eji.201243281 ID - Kim2013 ER - TY - JOUR AU - Patel, S. R. AU - Smith, K. AU - Letley, D. P. AU - Cook, K. W. AU - Memon, A. A. AU - Ingram, R. J. PY - 2013 DA - 2013// TI - Helicobacter pylori downregulates expression of human β-defensin 1 in the gastric mucosa in a type IV secretion-dependent fashion JO - Cell Microbiol VL - 15 UR - https://doi.org/10.1111/cmi.12174 DO - 10.1111/cmi.12174 ID - Patel2013 ER - TY - JOUR AU - Tenguria, S. AU - Ansari, S. A. AU - Khan, N. AU - Ranjan, A. AU - Devi, S. AU - Tegtmeyer, N. PY - 2014 DA - 2014// TI - Helicobacter pylori cell translocating kinase (CtkA/JHP0940) is pro-apoptotic in mouse macrophages and acts as auto-phosphorylating tyrosine kinase JO - Int J Med Microbiol VL - 304 UR - https://doi.org/10.1016/j.ijmm.2014.07.017 DO - 10.1016/j.ijmm.2014.07.017 ID - Tenguria2014 ER - TY - JOUR AU - Bumann, D. AU - Aksu, S. AU - Wendland, M. AU - Janek, K. AU - Zimny-Arndt, U. AU - Sabarth, N. PY - 2002 DA - 2002// TI - Proteome analysis of secreted proteins of the gastric pathogen H. pylori JO - Infect Immun VL - 70 UR - https://doi.org/10.1128/IAI.70.7.3396-3403.2002 DO - 10.1128/IAI.70.7.3396-3403.2002 ID - Bumann2002 ER - TY - JOUR AU - Roure, S. AU - Bonis, M. AU - Chaput, C. AU - Ecobichon, C. AU - Mattox, A. AU - Barrière, C. PY - 2012 DA - 2012// TI - Peptidoglycan maturation enzymes affect flagellar functionality in bacteria JO - Mol Microbiol VL - 86 UR - https://doi.org/10.1111/mmi.12019 DO - 10.1111/mmi.12019 ID - Roure2012 ER - TY - JOUR AU - Tegtmeyer, N. AU - Rivas Traverso, F. AU - Rohde, M. AU - Oyarzabal, O. A. AU - Lehn, N. AU - Schneider-Brachert, W. PY - 2013 DA - 2013// TI - Electron microscopic, genetic and protein expression analyses of Helicobacter acinonychis strains from a Bengal tiger JO - PLoS ONE VL - 8 UR - https://doi.org/10.1371/journal.pone.0071220 DO - 10.1371/journal.pone.0071220 ID - Tegtmeyer2013 ER - TY - JOUR AU - Tegtmeyer, N. AU - Wittelsberger, R. AU - Hartig, R. AU - Wessler, S. AU - Martinez-Quiles, N. AU - Backert, S. PY - 2011 DA - 2011// TI - Serine phosphorylation of cortactin controls focal adhesion kinase activity and cell scattering induced by Helicobacter pylori JO - Cell Host Microbe VL - 9 UR - https://doi.org/10.1016/j.chom.2011.05.007 DO - 10.1016/j.chom.2011.05.007 ID - Tegtmeyer2011 ER - TY - JOUR AU - Boehm, M. AU - Krause-Gruszczynska, M. AU - Rohde, M. AU - Tegtmeyer, N. AU - Takahashi, S. AU - Oyarzabal, O. A. PY - 2011 DA - 2011// TI - Major host factors involved in epithelial cell invasion of Campylobacter jejuni: role of fibronectin, integrin beta1, FAK, Tiam-1, and DOCK180 in activating Rho GTPase Rac1 JO - Front Cell Infect Microbiol VL - 12 ID - Boehm2011 ER - TY - JOUR AU - Zhang, X. S. AU - Tegtmeyer, N. AU - Traube, L. AU - Jindal, S. AU - Perez-Perez, G. AU - Sticht, H. PY - 2015 DA - 2015// TI - A specific A/T polymorphism in Western tyrosine phosphorylation B-motifs regulates Helicobacter pylori CagA epithelial cell interactions JO - PLoS Pathog VL - 11 UR - https://doi.org/10.1371/journal.ppat.1004621 DO - 10.1371/journal.ppat.1004621 ID - Zhang2015 ER - TY - JOUR AU - Hirsch, C. AU - Tegtmeyer, N. AU - Rohde, M. AU - Rowland, M. AU - Oyarzabal, O. A. AU - Backert, S. PY - 2012 DA - 2012// TI - Live Helicobacter pylori in the root canal of endodontic-infected deciduous teeth JO - J Gastroenterol VL - 47 UR - https://doi.org/10.1007/s00535-012-0618-8 DO - 10.1007/s00535-012-0618-8 ID - Hirsch2012 ER - TY - JOUR AU - Kumar Pachathundikandi, S. AU - Brandt, S. AU - Madassery, J. AU - Backert, S. PY - 2011 DA - 2011// TI - Induction of TLR-2 and TLR-5 expression by Helicobacter pylori switches cagPAI-dependent signaling leading to the secretion of IL-8 and TNF-α JO - PLoS ONE VL - 6 UR - https://doi.org/10.1371/journal.pone.0019614 DO - 10.1371/journal.pone.0019614 ID - Kumar Pachathundikandi2011 ER -