Table 3 Correlation of gut microbiota and immune indices: correlation between gut microbiota and serum immunoglobulin levels

From: Possible correlation between gut microbiota and immunity among healthy middle-aged and elderly people in southwest China

	Middle-aged group			Elderly group
	IgA	IgG	IgM	IgA	IgG	IgM
Phylum
Actinobacteria	0.023	− 0.012	− 0.069	0.001	0.157	0.137
Bacteroidetes	0.158	0.246*	0.218	− 0.125	− 0.102	− 0.062
Firmicutes	− 0.009	0.085	− 0.243*	0.102	0.041	0.086
Proteobacteria	− 0.021	− 0.208	0.154	0.004	− 0.119	0.131
Verrucomicrobia	− 0.049	− 0.011	0.001	0.428**	− 0.040	0.025
Bacteroidetes/Firmicutes	0.136	0.222*	0.243*	− 0.107	− 0.099	− 0.074
Richness/diversity
Chao	0.050	0.063	− 0.087	0.261*	0.094	− 0.145
Observed Species	0.092	0.083	− 0.065	0.280*	0.048	− 0.227
Shannon	0.083	0.093	0.020	0.199	− 0.043	− 0.020
Simpson	− 0.079	− 0.082	− 0.022	− 0.139	0.094	− 0.076

Spearman’s correlation coefficient was calculated between the presence of gut microbiota and serum immunoglobulin levels. * and ** indicate significant difference with a P value of < 0.05 and < 0.01, respectively. Observed species value and chao value can reflect the species richness of community. Shannon value and simpson value can reflect the species diversity of the community

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ISSN: 1757-4749

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