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Table 1 Baseline characteristics of patients with and without vancomycin resistant Enterococcus colonization who underwent testing with a gastrointestinal pathogen PCR panel or Clostridium difficile test

From: Gut colonization with vancomycin-resistant Enterococcus and risk for subsequent enteric infection

Variable

Total (n = 761)

No VRE (n = 630, 82.8%)

VRE (n = 131, 17.2%)

p value

Sex

 Male

387 (51%)

330 (52%)

57 (43.5%)

 

 Female

374 (49%)

300 (48%)

74 (56.5%)

0.07

Race

 Asian

31 (4.1%)

27 (4.3%)

4 (3.1%)

 

 Black

89 (11%)

77 (12%)

12 (9.2%)

 

 White

286 (38%)

231 (37%)

55 (42.0%)

 

 Other/unknown

355 (47%)

295 (47%)

60 (45.8%)

0.55

Ethnicity

 Hispanic

128 (17%)

114 (18%)

14 (10.7%)

 

 Non-hispanic

280 (37%)

220 (35%)

60 (45.8%)

 

 Unknown

353 (46%)

296 (47%)

57 (43.5%)

0.03

Age group

 18–29

58 (7.6%)

45 (7.1%)

13 (9.9%)

 

 30–49

137 (18%)

115 (18%)

22 (16.8%)

 

 50–69

366 (48%)

304 (48%)

62 (47.3%)

 

 > 70

200 (26%)

166 (26%)

34 (26.0%)

0.74

Residential zip code

 New York city

414 (54%)

342 (54%)

72 (55.0%)

 

 Tristate area

328 (43%)

273 (43%)

55 (42.0%)

 

 Other

19 (2.5%)

15 (2.4%)

4 (3.1%)

0.88

Laboratory values at VRE testing (median, IQR)

 Creatinine (mg/dL)

1.1 (0.8–2.1)

1.1 (0.7–1.1)

1.03 (0.8–2.0)

0.58

 Albumin (g/dL)

2.8 (2.4–3.2)

2.8 (2.4–3.2)

2.7 (2.3–3.1)

0.11

 White blood cell count (cells × 103/µL)

10 (6.5–14)

10 (6.5–14)

9.6 (6.3–14)

0.74

 Hematocrit (%)

33 (32–34)

33 (32–34)

33 (31–34)

0.19

 Platelets (× 103/µL)

138 (135–141)

138 (135–141)

137 (135–141)

0.11

Surgery after VRE test

246 (32%)

209 (33%)

37 (28%)

0.27

Mechanical ventilation after VRE test

450 (59%)

371 (59%)

79 (60%)

0.76

Immunosuppression exposure after VRE test

430 (57%)

348 (55%)

82 (63%)

0.12

Antibiotic exposure after VRE test

 Any antibiotic

719 (95%)

483 (77%)

131 (100%)

< 0.01

 Vancomycin IV

571 (75%)

467 (74%)

104 (79%)

0.21

 VRE-targeted therapy

15 (2.6%)

13 (2.7%)

2 (1.9%)

0.64

LOS (days; median, IQR)

 Hospital LOS

15 (8–31)

14 (7–29)

19 (10–44)

< 0.01

 Intensive care unit LOS

4 (2–8)

4 (2–8)

5 (3–9)

0.01

In-hospital mortality

52 (6.8%)

36 (5.7%)

16 (12%)

< 0.01