From: Gut colonization with vancomycin-resistant Enterococcus and risk for subsequent enteric infection
Variable | GI PCR | C. difficile PCR | ||
---|---|---|---|---|
Univariable HR | Multivariable HR | Univariable HR | Multivariable HR | |
Sex | ||||
Male | 0.71 (0.49–1.02) | 0.89 (0.60–1.31) | ||
Race | ||||
Asian | 0.99 (0.40–2.48) | 0.48 (0.12–2.00) | ||
Black | 0.68 (0.36–1.31) | 0.66 (0.32–1.34) | ||
White | 0.96 (0.65–1.40) | 0.87 (0.57–1.32) | ||
Other/unknown | Reference | Reference | ||
Ethnicity | ||||
Hispanic | 1.23 (0.77–1.98) | 1.16 (0.84–1.60) | ||
Non-hispanic | 0.91 (0.61–1.36) | 0.89 (0.68–1.17) | ||
Unknown | Reference | Reference | ||
Age group | ||||
18–29 | 0.54 (0.21–1.38) | 0.81 (0.34–1.95) | ||
30–49 | 1.17 (0.69–2.01) | 0.75 (0.39–1.44) | ||
50–69 | 0.99 (0.64–1.53) | 0.96 (0.61–1.50) | ||
> 70 | Reference | Reference | ||
Residential zip code | ||||
New York city | 0.40 (0.15–1.12) | 1.87 (0.26–13.51) | ||
Tristate area | 0.42 (0.15–1.16) | 1.84 (0.25–13.40) | ||
Other | Reference | Reference | ||
Laboratory values at VRE testing | ||||
Creatinine (mg/dL) | 0.89 (0.79–0.99) | 0.89 (0.79–1.01) | 0.98 (0.88–1.08) | |
Albumin (g/dL) | 1.08 (0.77–1.54) | 0.82 (0.58–1.17) | ||
White blood cell count (cell/mcL) | 1.01 (0.99–1.04) | 1.02 (0.99–1.05) | ||
Hematocrit (%) | 1.00 (0.97–1.03) | 0.97 (0.95–1.00) | ||
Platelets (/mcL) | 1.04 (1.01–1.08) | 1.01 (0.97–1.05) | 1.01 (0.97–1.06) | |
VRE colonization | 0.52 (0.28–0.96) | 0.47 (0.25–0.88) | 1.39 (0.83–2.27) | 1.32 (0.79–2.19) |
Surgery after VRE test | 1.02 (0.70–1.49) | 0.96 (0.63–1.48) | ||
Mechanical ventilation after VRE test | 1.18 (0.82–1.70) | 1.31 (0.88–1.95) | ||
Immunosuppression exposure after VRE test | 1.00 (0.70–1.44) | 1.10 (0.74–1.63) | ||
Antibiotic exposure after VRE testing | ||||
Any antibiotic | 0.93 (0.59–1.49) | 1.20 (0.74–1.93) | ||
VRE–targeted therapy | 0.72 (0.23–2.26) | 1.02 (0.25–4.18) | ||
LOS | ||||
Hospital LOS | 1.01 (1.00–1.01) | 1.00 (0.99–1.01) | ||
ICU LOS | 1.01 (1.00–1.03) | 1.02 (1.01–1.04) | 1.02 (1.01–1.04) | |
In-hospital mortality | 0.93 (0.41–2.13) | 1.37 (0.50–3.72) | ||
Place of GI PCR test | ||||
Emergency department | 0.85 (0.45–1.61) | |||
Endoscopy | 1.56 (0.37–6.60) | |||
Inpatient | 0.87 (0.58–1.30) | |||
Outpatient | Reference |