The microbiome of Crohn’s disease aphthous ulcers

Table 1 Patient and sample characteristics

Sample ID	Age (years)	Gender	Disease status	Biopsy location	Years since diagnosis	Montreal location	Montreal behaviour	Antibiotics	Indication for colonoscopy (controls)
1SBAU	40	M	CD	TI ulcer	8	L1	B1	N
1SB				CM
2SBAU	29	F	CD	TI ulcer	7	L3	B1	N
2SB				TI
3LBAU	37	M	CD	SIG ulcer	18	L2	B1	N
3LB				AC
4SBAU	32	M	CD	TI ulcer	3	L3	B2p	N
4SB				TI
5LBAU	30	M	CD	SIG ulcer	6	L3	B1	N
5LB				SIG
6RECAU	50	F	CD	REC ulcer	0	L2	B1	Y
6REC				REC
7LBAU	40	M	UC	SIG ulcer	25	E3	S2	N
7LB				DC
8SBAU	34	F	CD	CM ulcer	15	L3	B2	N
8SB				ICV
9SBAU	22	F	CD	CM ulcer	0	L3	B1	N
9SB				CM
10RECAU	22	F	CD	REC ulcer	0	L3	B1	N
10REC				REC
11SBAU	50	M	CD	TI ulcer	10	L3	B3p	N
11SB			CD	TI
12LBAU	28	M	CD	SIG ulcer	15	L3	B2	Y
12LB				DC
NB1	58	M	NC	DC	–				Rectal bleeding
NB2	31	F	NC	AC	–				Constipation
NB5	55		NC	TI	–				Altered bowel habit
NB11	33	M	NC	TI	–				Diarrhoea
NB12	38	M	NC	TI	–				Rectal bleeding
NB13	35	M	NC	REC	–				Rectal bleeding
NB15	57	M	NC	TI	–				Rectal bleeding, abdominal pain
NB17	43	M	NC	TI	–				Rectal bleeding
NB18	34	M	NC	TI	–				Rectal bleeding, FHCRC
NB21	53	F	NC	TI	–				Bloating, abdominal pain
NB23	43	M	NC	TI	–				FHCRC
NB26	60	F	NC	SIG	–				Rectal bleeding
NB27	58	M	NC	TI	–				Polyp surveillance
NB29	37	F	NC	TI	–				Cancer surveillance
NB37	48	F	NC	TI	–				Fever of unknown origin
NB39	31	F	NC	TI	–				Abdominal pain
NB48	20		NC	AC	–				Rectal bleeding

CD Crohn’s disease, UC ulcerative colitis, NC normal control, AU aphthous ulcer, SB small bowel, LB large bowel, REC rectum, SIG sigmoid colon, DC descending colon, AC ascending colon, ICV ileocaecal valve, CM caecum, TI terminal ileum, NB normal (mucosa) biopsy, F female, M male, L1 ileal CD, L2 colonic CD, L3 Ileocolonic CD, E3 pancolitis ulcerative colitis (proximal to splenic flexure), B1 non-stricturing non-penetrating, B2, structuring, B3 penetrating, p perianal disease, N ‘no’, Y ‘yes’ FHCRC, family history of colorectal cancer

ISSN: 1757-4749