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Table 3 Predicted proteins encoded by inserted DNA adjacent to pheV, pheU or selC

From: Determination of virulence and fitness genes associated with the pheU, pheV and selC integration sites of LEE-negative food-borne Shiga toxin-producing Escherichia coli strains

Proteins

TS18/08

RF1a

K30

17584/1

pheV

pheU

pheU

pheV

selC

Mobile elements

x

x

x

x

x

Transporters

 SapAa

  

x

x

x

 ShiA-homologa

   

x

x

 Per-activated serine protease autotransporter enterotoxin EspC

   

x

 

 Outer membrane porin OmpF

x

  

x

 

 Antigen 43a

x

  

x

 

Ato system

 AtoS/AtosC

   

x

 

 AtoC

   

x

 

 AtoD

   

x

 

 AtoA

   

x

 

 AtoE

   

x

 

 AtoBa

   

x

 

Type IV toxin-antitoxin system

 YeeP/NgrBa

x

x

 

x

x

 YeeRa

   

x

 

 YeeSa

x

x

 

x

x

 YeeTa

x

x

 

x

x

 YeeUa

x

x

 

x

x

 YeeVa

x

x

 

x

x

Domains of unknown function

 DUF3987 containing protein

 

x

   

 DUF957 containing proteina

 

x

x

x

 

 DUF4338 containing protein

  

x

  

 DUF4222 containing protein

x

    

 DUF2251 containing protein

   

x

 

 DUF1705 containing protein

    

x

 DUF2569 containing protein

    

x

Methyltransferases

 Z1226a

x

x

x

x

x

 DNA-cytosine methyltransferase

    

x

B12 uptake system

 TonB-dependent receptora

x

  

x

 

 Outer membrane vitamin B12 receptor BtuB

x

  

x

 

Hemolysin/hemagglutinin

 Putative member of ShlA/HecA/FhaA exoprotein family

    

x

 Putative large exoprotein involved in heme utilization or adhesion of ShlA/HecA/FhaA family

x

 

x

 

x

 Putative adhesin/hemagglutinin/hemolysin

x

   

x

 RTX toxin activating lysine-acyltransferase

x

    

 Hemolysin expression modulating protein

x

  

x

 

 Hemolysin activator protein precursora

    

x

Regulators

 DNA-binding proteinsa

x

x

  

x

 dNTP triphosphohydrolase

 

x

   

 Transcriptional regulatorsa

 

x

x

x

x

 HecB-like protein

x

    

 ProQ/FINO family protein

x

    

Others

 Helicasesa

x

x

x

  

 YkfFa

 

x

 

x

x

 YafZa

x

x

 

x

x

 Inovirus Gp2 family proteina

x

x

 

x

 

 Outer membrane protein X precursor

x

    

 KlcAa

x

x

 

x

x

 Z5092a

 

x

x

  

 EAL domain-containing protein

 

x

   

 N-acetylgalactosamine 6-sulfate sulfatase (GALNS)

x

  

x

 

 Lipoprotein bor

x

    

 YfjI

x

  

x

 

 Ash family protein

   

x

 

 Restriction endonuclease

    

x

 Putative phosphoethanolamine transferasea

x

x

x

x

x

 l-lactate permease

x

    

 Aec62a

   

x

 

 Putative competence protein

  

x

  

Hypothetical proteins

x

x

x

x

x

  1. x = putative gene is present in the corresponding tRNA locus
  2. aGrouped or partly grouped as virulence factors by RASTk analysis