Fig. 2

Maximum changes in CfaB- and YghJ-specific serum IgA and IgG/IgM responses. The numbers represent each volunteer’s study ID number (e.g. “10” = “EV10”). Open circles (○) represent the three volunteers who did not have TW11681 proliferation peaks in their stools, while closed circles (●) represent the six who did. The Y-axis values are plotted logarithmically and represent the maximum values of the median fluorescence intensity (MFI) of assay results based on serum collected 10 and 28 days after infection, minus the MFI of assay results based on the serum collected before the volunteer had ingested the dose. Prior to this calculation, MFI of assays results based on the negative controls were subtracted from all values