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Fig. 2 | Gut Pathogens

Fig. 2

From: Campylobacter jejuni enters gut epithelial cells and impairs intestinal barrier function through cleavage of occludin by serine protease HtrA

Fig. 2

Tight junction protein distribution in intestinal biopsies from healthy individuals and campylobacteriosis cases. Confocal laser-scanning microscopy of human colon crypts from a non-infected individual (a, b) and an acute C. jejuni infection (c, d). The images show clockwise immunostaining for zonula occludens protein-1 (ZO-1, green), occludin (red), nuclei by use of DAPI staining (blue) and a merged image in which co-localization of the tight junction proteins ZO-1 and occludin appears as yellow. White arrows indicate redistributed occludin signals in the infected biopsies

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