Fig. 6From: Campylobacter jejuni enters gut epithelial cells and impairs intestinal barrier function through cleavage of occludin by serine protease HtrAQuantification of cell-associated (adhesion) and intracellular (invasion) levels of C. jejuni infecting Caco-2 wild-type (wt) and occludin knockout cells. The two cell lines were infected for 12 h with the indicated strains using an MOI of 100. The total number of cell-associated (a) and intracellular bacteria (b) was determined by gentamycin protection assay. The adhesion and invasion levels were dependent on the cell type and expression of the htrA gene. n = 9, p < 0.05 (*), p < 0.01 (**), p < 0.0001 (****), Mann–Whitney test. Data represented mean ± SEMBack to article page